Mechanisms Underlying Cardiovascular Consequences Associated With COVID-19 and Long COVID
Reason given: Funding not available
Key facts
- Where
- New York, United StatesSee the site
Where in United States
- CUIMCNew York, United StatesNo longer taking part
Trial details
- Who runs it
- Columbia University
- Trial code
- NCT06427512
- Record updated
- 24 May 2024
- Original description
AIM 1. Characterize cardiovascular phenotypes of long COVID by cardiopulmonary, meta-bolic, and cardiac mechanical/physiological responses to exercise and microvascular vasomotor function.Read full original descriptionShow less
Mechanisms Underlying Cardiovascular Consequences Associated With COVID-19 and Long COVID - Characterizing Long COVID Phenotypes Using Physiological and Molecular Studies
AIM 1. Characterize cardiovascular phenotypes of long COVID by cardiopulmonary, meta-bolic, and cardiac mechanical/physiological responses to exercise and microvascular vasomotor function.
AIM 2. Identify intercellular signaling between immune cells and cardiac cells associated with microvascular phenotypes of long COVID.
Inclusion: Age > 18, < 75 yrs; History of lab-confirmed COVID; Symptomatic at >12 wks post-acute COVID (cases); Recovered by 8wks post-acute COVID (controls).
Exclusion: Any history of critical illness; Chronic kidney disease, Stage >4; Pre-COVID: HFrEF, CABG, arrhythmia; pulmonary hypertension, pulmonary embolus, interstitial lung disease (ILD), O2 dependence; dementia, stroke, autonomic dysfunction; coagulopathy; Post-COVID: ILD, O2 dependence.