Tests a heart pacing feature in adults with heart failure
Studies a timing feature for heart pacing in adults with heart failure.
Plain-language title generated from the registry record
Registry title: Acute Response to Left Bundle Branch Area Pacing With SyncAV
Key facts
- Where
- San Donato Milanese, ItalySee the site
Where in Italy
- I.R.C.C.S. Policlinico San DonatoSan Donato Milanese, ItalyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Abbott Medical Devices
- Trial code
- NCT06436053
- Record updated
- 9 July 2026
- Original description
This clinical investigation is a prospective, single-arm, post-market, non-randomized, single-center study designed to evaluate the effectiveness of the SyncAV CRT dynamic atrioventricular (AV) delay feature when used with left bundle branch area pacing (LBBAP).Read full original descriptionShow less
Acute Response to Left Bundle Branch Area Pacing With SyncAV
This clinical investigation is a prospective, single-arm, post-market, non-randomized, single-center study designed to evaluate the effectiveness of the SyncAV CRT dynamic atrioventricular (AV) delay feature when used with left bundle branch area pacing (LBBAP).
Inclusion: Patient is 18 years of age and willing to comply with the study requirements; Patients with approved indication for dual-chamber pacing or cardiac resynchronization therapy and scheduled to be implanted with an Abbott pacing system; Patient has documented left bundle branch block (LBBB) or intraventricular conduction delay (IVCD); Patient has an intrinsic QRS duration ≥ 130 ms; Patient has intact AV conduction with PR interval ≤ 250 ms.
Exclusion: Patient has had a recent myocardial infarction, ablation, electrolyte imbalance, or any condition within the last 90 days that would contraindicate for pacing device programming changes in the opinion of the investigator; Patient has other medical, anatomic, comorbid, social, or psychological conditions that, in the investigator's opinion, could limit the subject's ability to participate in the clinical investigation or to comply with follow-up requirements, or impact the scientific soundness of the clinical investigation results; Patient has a resting ventricular rate > 100 bpm; Patient has AV Block (2nd or 3rd degree); Patient has documented persistent atrial tachycardia or atrial fibrillation; Patient is currently participating in another clinical investigation; Patient is pregnant or nursing; Patient does not have legal authority; Patient is unable to read or write.