Heart failure trials in Italy

In Italy 103 Also abroad 1261

103 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 10 November 2026. Ask the study team whether a trial fits you.

Phase 2Not yet taking people in Italy
A Study of Bimagrumab in Participants With HFpEF
Where
Caserta, Torino
Age
18 years and over
People
540 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07920887 · EU 2026-527983-34-00
No phaseTaking people
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
Where
Turin
Age
18 years and over
People
850 worldwide
Run by
Abbott Medical Devices
See details and how to joinNCT06526195
No phaseTaking people
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
Where
Ancona, Bari, Bergamo, Bologna, Brescia, Castrovillari, Cotignola, Lecce, Milan, Monza, Pisa, Taranto, Udine
People
20,000 worldwide
Run by
Medtronic
See details and how to joinNCT00271180
No phaseTaking people
Heart Failure and Aortic Stenosis Transcriptome
Where
Milan, San Donato Milanese
Age
40 years to 75 years
People
500
Run by
IRCCS Policlinico S. Donato
See details and how to joinNCT03268135
Phase 3Taking people
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
Where
Arzignano, Bergamo, Brescia, Ferrara, Milan, Perugia, Rimini, Rome, Sesto San Giovanni
Age
18 years to 85 years
People
1,800 worldwide
Run by
Cytokinetics
See details and how to joinNCT06736574 · EU 2024-519219-32-00
Phase 2/3Taking people
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
Where
Bergamo, Bologna, Florence, Genoa, Milan, Padova, Rome, Turin
Age
29 days to 17 years
People
342 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT05714085 · EU 2022-501238-52-00
Phase 3Taking people
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
Where
Bari, Bergamo, Brescia, Cortona AR, Foggia, Forlì, Milan, Naples, Parma, Pavia, Rimini, Rivoli, Roma, Sassari
Age
18 years to 99 years
People
5,056 worldwide
Run by
Amgen
See details and how to joinNCT07037459
No phaseNot yet taking people in Italy
Metabolic Changes in Heart Failure Patients Treated With Vericiguat
Where
Potenza
Age
18 years and over
People
30
Run by
University of Salerno
See details and how to joinNCT07901270
Phase 3Taking people
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
Where
Bergamo, Foggia, Genoa, Naples, Pavia, Rome, Rozzano
Age
18 years and over
People
6,712 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT06424288 · EU 2023-509706-30-00
Phase 3Taking people
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
Where
Bergamo, Naples, Pavia, Pisa, Rome, Rozzano
Age
18 years and over
People
4,200 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT06935370 · EU 2024-519525-38-00
Phase 3Taking people
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity (MARITIME-HF)
Where
Bari, Bergamo, Brescia, Cortona, Foggia, Forli', Milan, Naples, Parma, Pavia, Rimini, Rivoli, Rome, Rozzano, Sassari
Age
18 years and over
People
2,787 worldwide
Run by
Amgen Inc.
See details and how to join2024-516654-22-00 · EU 2024-516654-22-00
Phase 3Taking people
A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction
Where
Bergamo, Bologna, Genoa, Milan, Naples, Padova, Rome, Turin
Age
Up to 18 years
People
117 worldwide
Run by
Bayer
See details and how to joinNCT07192952 · EU 2024-519830-22-00
No phaseTaking people
BIO|STREAM.CSP Study
Where
Bergamo, Brindisi, Milan, Novara, Piove di Sacco, Roma, Taranto
Age
18 years and over
People
1,000 worldwide
Run by
Biotronik SE & Co. KG
See details and how to joinNCT07393009
Phase 3Taking people
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
Where
Alexandria, Bari, Bergamo, Brescia, Chiavari, Ferrara, Foggia, Milan, Monza, Naples, Novara, Orbassano, Palermo, Pavia, Potenza, Rome, Rozzano, Siena, Turin, Udine
Age
40 years and over
People
11,300 worldwide
Run by
AstraZeneca
See details and how to joinNCT06677060 · EU 2024-514506-32-00
Phase 3Taking people
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
Where
Ancona - Torrette, Bologna, Bolzano, Brescia, Cona, Florence, Ivrea, Lecco, Messina, Milan, Naples, Orbassano, Palermo, Pavia, Perugia, Pisa, Roma, Rome, San Donato Milanese, Trieste
Age
18 years and over
People
1,280 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07207811
No phaseTaking people
CytOSorb TreatMent Of Critically Ill PatientS Registry
Where
Roma, San Giovanni Rotondo
People
3,000 worldwide
Run by
CytoSorbents, Inc
See details and how to joinNCT05146336
No phaseTaking people
Drug Management in Heart Failure
Where
Rome
Age
18 years and over
People
450
Run by
IRCCS San Raffaele Roma
See details and how to joinNCT06915584
No phaseTaking people
The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C)
Where
Roma
Age
18 years and over
People
754 worldwide
Run by
Sunnybrook Health Sciences Centre
See details and how to joinNCT05427370
No phaseTaking people
Estimation of Cardiovascular Risk in Patients With Crohn's Disease and Ulcerative Colitis (PROVACI)
Where
San Donato Milanese
Age
16 years and over
People
600
Run by
IRCCS Policlinico S. Donato
See details and how to joinNCT07095634
Phase 4Taking people
Pharmacological Optimization in Prevention in Heart Failure: A Sex-gap?
Where
Ancona, Cecina, Ferrara, Florence, Milan, Pisa, Ravenna, Reggio Emilia, Roma, San Donato Milanese
Age
18 years to 85 years
People
368
Run by
IRCCS Policlinico S. Donato
See details and how to joinNCT07295522
Phase 3Taking people
A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction
Where
Bergamo, Bologna, Genoa, Milan, Naples, Padova, Rome, Turin
Age
6 months to 17 years
People
111 worldwide
Run by
Bayer
See details and how to joinNCT07188805 · EU 2024-519829-38-00
Phase 3Taking people
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
Where
Acquaviva delle Fonti, Bari, Bergamo, Brescia, Catania, Catanzaro, Cona, Cortona, Florence, Milan, Novara, Pavia, San Giovanni Rotondo
Age
18 years to 130 years
People
3,850 worldwide
Run by
AstraZeneca
See details and how to joinNCT06307652 · EU 2023-508162-15-00
No phaseTaking people
Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)
Where
Ancona, Bergamo, Milan
Age
22 years and over
People
400 worldwide
Run by
Reprieve Cardiovascular, Inc
See details and how to joinNCT06898515
No phaseTaking people
Artificial Voice Analysis and Telemonitoring for Heart Failure. A Feasibility Study
Where
Milan
Age
18 years and over
People
60
Run by
Niguarda Hospital
See details and how to joinNCT07664748
No phaseTaking people
A Study to Learn About the Use of Acoramidis in Patients With a Heart Condition Called Transthyretin Amyloid Cardiomyopathy (ATTR-CM) in a Real-world Setting
Where
Multiple Locations
Age
18 years and over
People
2,000 worldwide
Run by
Bayer
See details and how to joinNCT07235462