Tests how short sleep affects people whose parents have high blood pressure
Compares partial sleep restriction with normal sleep in young adults with hypertensive parents.
Plain-language title generated from the registry record
Registry title: Sleep Restriction and Parental History of Hypertension
Key facts
- Where
- Rochester, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 35 years old?
Source: NCT06482814, who can take part
Where in United States
- Mayo Clinic in RochesterRochester, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Mayo Clinic
- Trial code
- NCT06482814
- Record updated
- 13 August 2026
- Original description
The purpose of this study is to research the effects of partial sleep deprivation (sleep restriction) in a group of individuals whose parents have high blood pressure compared to a group of individuals whose parents have normal blood pressure.Read full original descriptionShow less
Sleep Restriction and Parental History of Hypertension
The purpose of this study is to research the effects of partial sleep deprivation (sleep restriction) in a group of individuals whose parents have high blood pressure compared to a group of individuals whose parents have normal blood pressure.
Inclusion: Healthy adults aged 18-35 years; Absence of any significant medical or psychiatric disease (as per the investigators' judgment); Nonsmoker; Nonpregnant; History of normal sleep duration (reported average sleep duration between 7-9 hours/night and no habitual napping); Hypertension status information available for both biological parents; Ability to understand study procedures and to comply with them for the entire length of the study; Ability to understand English and provide informed consent.
Exclusion: Use of tobacco, vaping, marijuana products or other drugs; Regular use of prescription medications other than contraceptives; Unable to determine history of HTN in participant's biological parents or subject being adopted; History of significant medical or psychiatric disorders (as per the investigators' judgment); Restless leg syndrome (as per the Cambridge-Hopkins questionnaire); Fasting glucose ≥126 mg/dl; Exclusionary for blood draws: hemoglobin <11.6 g/dL in women / <13.2 g/dL in men; participants with measured hemoglobin levels below these thresholds will be allowed to continue participate in study tests and procedures not involving blood draws; Age <18 or >35 years; Body mass index <18.5 or ≥30 kg/m2; Pregnant or lactating; Excessive caffeine consumption (>400 mg/day); Excessive alcohol consumption (>7 drinks/week for women, >14 drinks/week for men); Office SBP/DBP ≥130/80 mmHg; Daytime ambulatory SBP/DBP ≥130/80 mmHg; Glomerular filtration rate <60 mL/min/BSA; Use of melatonin supplements or any other over-the-counter sleep aid; Moderate-to-severe sleep disordered breathing (apnea/hypopnea index, AHI ≥15) or mild sleep disordered breathing (AHI 5-15) with daytime sleepiness (Epworth Sleepiness Scale >10); Moderate-to-severe insomnia (Insomnia Severity Index >14); Excessive daytime sleepiness (Epworth Sleepiness Scale >15); Extreme chronotype (Morningness-Eveningness Questionnaire >69 or <31); Night shift work; Ongoing participation in other research studies (as per the investigators' judgment); Any other medical, geographic, or social factor making study participation impractical; Not English-speaking and/or inability to provide informed consent.