Frontlight ResearchEarly access
Active, not recruitingNo phase
Positive Minds Strong Joints for Knee Osteoarthritis
Key facts
- Who runs it
- Boston University Charles River Campus
- Where
- Boston, United StatesSee the site
- Trial code
- Status
- Active, not recruiting
- People taking part
- 39 people enrolled
- Started
- 17 Feb 2025
- Expected to end
- 30 Dec 2026
- Type of study
- Interventional
- Treatments tested
- Positive Minds, Strong Joints
- Record updated
- 11 August 2026
Who can take part
- Age
- 50 years and older
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 25 criteriaShow less
Who can take part
- Age≥50
- BMI ≤ 40 kg/m2
- Self-identify as Black (including African American)
- Knee pain ≥4/10 on a 11 numeric scale over the past week
- Scored 5 or more on either the Patient Health Questionnaire (PHQ-9) and/or the Generalized Anxiety Disorder 7-item Scale (GAD-7)
- Can speak and understand English at a sufficient level to understand the study procedures and informed consent
- Available for study duration
- Able to attend remote sessions
Who cannot take part
- Intra-articular corticosteroid or hyaluronic acid knee injection within 3 months
- Knee surgery within past 6 months
- Currently receiving or received within 3-months any PT for knee OA
- Currently receiving or received within 3 months any mental health intervention (excluding pharmacologic treatments)
- Planning to initiate physical therapy for joint or low back pain in the next 3months
- Planning for a major surgery in the next 6 months
- Receiving chemotherapy or radiation therapy for cancer (except non-melanoma skin cancer)
- Neurologic conditions (e.g., stroke, Parkinson's disease, etc.)
- Having high risk mental health symptoms (active suicidality, bipolar disorder, mania, psychosis, schizophrenia)
- Knee, hip or ankle replacement
- Planning to initiate any mental health treatment (excluding pharmacologic treatments) in the next 1 month
- Systemic inflammatory arthritis (e.g., rheumatoid arthritis)
- Contraindications to starting an exercise program
- Suspected substance abuse
- Lack capacity to consent
- Pregnancy (self-report)
- Participation in another clinical trial for any joint or muscle pain
Where in United States
- Boston UniversityBoston, United States
About the trial
What the trial wants to find out
The aim of this research study is to test the feasibility of a physical and mental health intervention (Positive Minds, Strong Joints or PMSJ) for Black adults with knee osteoarthritis (OA).
The group in the trial
- Positive Minds Strong JointsTreatment being tested
Participants will receive an individual mental health intervention and a group-based exercise intervention through a HIPPAA-Protected Zoom videoconferencing once a week for 10 weeks.
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Physical and Mental Health Intervention for Black Adults With Knee Osteoarthritis: A Feasibility Study
- Record updated
- 11 August 2026