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Sleep treatment adapted for veterans with PTSD and sleep problems

Tests an adapted sleep treatment in veterans with PTSD and disturbed sleep.

Key facts

Who runs it
VA Office of Research and Development
Where
San Francisco, United StatesSee the site
Trial code
Registry title
A Transdiagnostic Sleep Health Intervention for Veterans With PTSD
Status
Not yet recruiting
People taking part
182 people, planned
Starts
1 Jan 2027
Expected to end
31 Jan 2029
Type of study
Interventional, 2 groupsOne group gets an existing treatment, for comparison.
Treatments tested
  • TranS-C for PTSD
  • Sleep Psychoeducation Control
Record updated
6 November 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for U.S. military Veterans with PTSD and sleep problems (insomnia and nightmares) who get VA care. It tests a sleep treatment delivered by video.

Age
18 Years and older
Sex
All sexes can join
Disease stage
PTSD diagnosis on the CAPS-5 interview, or CAPS 5 score >=25 without full criteria. Insomnia disorder with an Insomnia Severity Index (ISI) score >=10. CAPS-IV nightmare score >=4. Daily life affected by poor sleep, with a WHODAS score >=32.
Earlier treatment
People now in a sleep-focused talk therapy, or planning to start one in the next 3 months, cannot join. Examples are CBT-I, BBT-I and IRT.

Main reasons for not taking part

  • Current memory or thinking problems, active psychosis or mania, or moderate to severe neurodegenerative disease that prevents video therapy or secure email
  • No reliable internet on a computer, iPad or similar device (a telephone is not enough)
  • Unable or unwilling to use a VA-approved video platform and VA secure email
  • Now in, or planning within 3 months, a sleep-focused talk therapy
  • Not willing to attend 8-12 treatment sessions

The registry criteria, word for word

Show all 10 criteriaShow less

Who can take part

  • U.S. Military Veteran engaged in VA primary and/or mental health care
  • Clinician-Administered post-traumatic stress disorder (PTSD) Scale (CAPS-5) PTSD diagnosis; or CAPS 5 score >=25 in the absence of full criteria
  • SCID Insomnia Disorder diagnosis, supported by Insomnia Severity Index (ISI) score >=10
  • CAPS-IV nightmare score >=4
  • Sleep-related functional impairment based on a World Health Organization Disability Assessment Schedule (WHODAS) score >=32
  • Willingness to engage in 8-12 sessions of treatment to address their sleep disturbance

Who cannot take part

  • Current engagement in a sleep-focused psychotherapy, or plan to start a sleep-focused psychotherapy in the next 3 months. Sleep-focused psychotherapies include, but are not limited to, cognitive behavioral therapy for insomnia (CBT-I), brief behavioral treatment for insomnia (BBT-I), and imagery rehearsal therapy (IRT)
  • Current cognitive problems, active psychosis or mania, or other mental/cognitive conditions such as moderate to severe neurodegenerative disease that would render the participant unable to connect to videoconferencing platform, engage in remote psychotherapy, or communicate using the required VA secure email platform
  • No access to reliable internet service connected to a computer, iPad or similar device (telephone not adequate)
  • Inability or unwillingness to use a VA-approved videoconferencing platform and VA secure email

Where in United States

  • San Francisco VA Medical Center, San Francisco, CASan Francisco, United StatesContact: Emily J BergNot yet recruiting

About the trial

What the trial wants to find out

Sleep disturbance is a major problem in Veterans with posttraumatic stress disorder (PTSD). This study will test a version of a sleep treatment that's been shown to be effective in the general population, with some changes to tailor it to the needs of Veterans with PTSD and sleep disturbance.

The 2 groups in the trial

  • Arm 1: ExperimentalTreatment being tested

    Participants receiving experimental TSC-PTSD treatment.

    Treatment: TranS-C for PTSD

  • Arm 2: Active ControlExisting treatment, for comparison

    Participants receiving sleep psychoeducation control.

    Treatment: Sleep Psychoeducation Control

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
A Randomized, Controlled Trial of a Modified Sleep and Circadian Intervention for Veterans With PTSD: Advancing Psychosocial Rehabilitation Through Sleep Health
Plain-language title
Sleep treatment adapted for veterans with PTSD and sleep problemsGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 14 November 2026.
Record updated
6 November 2026