Adding sleep treatment to exercise coaching for knee osteoarthritis pain and insomnia
Tests whether insomnia treatment plus exercise coaching eases knee pain in older adults.
Key facts
- Who runs it
- University of Michigan
- Where
- Ann Arbor, United StatesSee the site
- Trial code
- Registry title
- Move and Snooze: Adding Insomnia Treatment to an Exercise Program to Improve Pain Outcomes in Older Adults With Knee Osteoarthritis
- Status
- Recruiting
- People taking part
- 288 people, planned
- Started
- 4 Nov 2024
- Expected to end
- 31 Aug 2028
- Type of study
- Interventional, 2 groups
- Treatments tested
- Personalized exercise coaching
- Cognitive behavioral therapy for Insomnia
- Record updated
- 13 April 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults aged 50 or older with knee osteoarthritis pain and ongoing insomnia. It compares online exercise coaching with or without a sleep therapy (CBT-I).
- Age
- 50 Years and older
- Sex
- All sexes can join
- Disease stage
- Knee osteoarthritis diagnosed by a doctor, with lasting knee pain of at least moderate strength, and lasting insomnia symptoms.
- Earlier treatment
- If you take medicine for pain or sleep, the prescription must not have changed in the previous three months. No other changes during the study. No interventional trial or pain or sleep program in the past six months.
- Biomarker or test result
- Insomnia shown by the score on the Sleep Condition Indicator questionnaire.
Main reasons for not taking part
- Rheumatoid arthritis or another inflammatory joint disease, active cancer, or a neurological condition
- A doctor advised you to avoid physical activity
- Significant memory or thinking problems, or a severe psychiatric disorder
- Shift work or another irregular sleep schedule, or an untreated sleep disorder like sleep apnea
- Already meeting U.S. physical activity guidance
The registry criteria, word for word
Show all 19 criteriaShow less
Who can take part
- Self-reported physician diagnosis of knee osteoarthritis
- Persistent knee osteoarthritis-related pain of at least moderate intensity (as indicated in the protocol)
- Indication of persistent symptoms of insomnia, determined by scoring on the Sleep Condition Indicator questionnaire (as indicated in the protocol)
- If receiving medication for pain or sleep disturbances, having had no change in prescription in the previous three months and be willing to make no other changes to medications for pain or sleep during the active study period
- Adequate literacy level to ensure web-based surveys can be completed independently, as assessed using a brief 3-item literacy level screener
Who cannot take part
- Concurrent diagnosis of a systemic, inflammatory musculoskeletal disorder (e.g., rheumatoid arthritis)
- Serious physical health concerns necessitating surgery or with a prognosis <6 months
- Active malignancy
- Neurological conditions (e.g., movement disorders)
- Any medical condition which would make graded increase of physical activity unsuitable (determined by a positive answer to the question: "Has a doctor or healthcare professional advised you to avoid physical activity for any reason?")
- Evidence of significant cognitive impairment (i.e., ≥2 errors on a 6-item cognitive screener)
- Presence of severe psychiatric disorder
- Visual or hearing impairment that would prevent use of the intervention
- Self-report of diagnosis of a specific sleep disorder other than insomnia that is not currently adequately treated, e.g., sleep apnea or narcolepsy
- Unable to understand English sufficiently to take part in the intervention
- Unable to provide electronic informed consent
- Currently participating in an interventional trial or a pain or sleep management program or having done so in the past six months
- Irregular sleep-wake schedule, e.g., shift work
- Currently meeting or exceeding physical activity guidance from the U.S. Department of Health and Human Services (noted in protocol)
Where in United States
- University of MichiganAnn Arbor, United StatesContact: Jade TrederTaking people
About the trial
What the trial wants to find out
This research will compare the effectiveness of a remotely delivered personalized exercise coaching plus an evidence-based sleep improvement intervention to remotely delivered personalized exercise coaching alone for knee osteoarthritis pain.
Read full original descriptionShow less
The study team hypothesize that the combined intervention will result in greater improvements in patient-reported pain intensity, recorded with real-time data capture, than remotely delivered exercise coaching alone.
The 2 groups in the trial
- Move and Snooze programTreatment being tested
This includes the personalized exercise program plus Cognitive Behavioral Therapy for Insomnia (CBT-I).
Treatment: Personalized exercise coaching and Cognitive behavioral therapy for Insomnia
- Personalized exercise programTreatment being tested
Treatment: Personalized exercise coaching
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Move and Snooze: Adding Insomnia Treatment to an Exercise Program to Improve Pain Outcomes in Older Adults With Knee Osteoarthritis
- Plain-language title
- Adding sleep treatment to exercise coaching for knee osteoarthritis pain and insomniaGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 14 November 2026.
- Record updated
- 13 April 2026