Analysis of the Loss of Muscle Force, Power and Motor Control to Predict the Risk of Falls in Patients With Knee OA
Key facts
- Who runs it
- Istituto Ortopedico Rizzoli
- Where
- Bologna, ItalySee the site
- Trial code
- Status
- Recruiting
- People taking part
- 50 people, planned
- Started
- 30 Jan 2025
- Expected to end
- 30 Jun 2029
- Type of study
- Interventional
- Treatments tested
- Muscle power assessment
- Muscle force assessment
- Home-based mobility monitoring
- Magnetic Resonance Imaging
- Gait assessment
- Record updated
- 9 November 2026
Who can take part
- Age
- 65 years to 80 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 12 criteriaShow less
Who can take part
- Age between 65 and 80 years
- Kellgren score II e III
- No history of falls in the last 12 months
Who cannot take part
- Previous interventions or traumas to the joints of the lower limb
- Any musculoskeletal, neurological, rheumatic or tumoral diseases
- Dementia
- Diabetes
- Severe Hypertension (Level 3)
- Severe Cardio-pulmonary insufficiency
- Pathologies or physical conditions incompatible with the use of magnetic resonance imaging and electrostimulation (i.e., active and passive implanted biomedical devices, epilepsy, severe venous insufficiency in the lower limbs)
- Inguinal or abdominal hernia
- Diagnosis of Osteonecrosis in the lower limb joints
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 65 and 80 years old?
Where in Italy
- IRCCS Istituto ortopedico RizzoliBologna, ItalyContact: Lisa Berti, ProfessorTaking people
About the trial
What the trial wants to find out
The twofold goal of this study is to understand the link between muscle power, muscle strength, and muscle control degradation with the risk of falling, and to develop a framework for the comprehensive and quantitative assessment of muscle power (and strength) in an elderly population of patients with knee osteoarthritis, who are at higher risk of falling. The main question it aims to answer is:
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● Are muscle power and motor control degradation better predictors of falls than muscle strength in the aging population?
Participants will undergo:
* Muscle force assessment on a dynamometer * Muscle power assessment on a dynamometer and on isntrumented stairs * Home-based mobility monitoring * Full lower limb MRI acquisition * Gait assessment
The group in the trial
- Knee OsteoarthritisTreatment being tested
Elderly patients with knee osteoarthritis, without a history of falls (in the 12 months prior to enrollment). All subjects will be followed up for 24 months, every 6 months. Muscle force and power assessments, plus a home-based mobility monitoring, will be performed at all visits. Full lower limb MRI and a gait assessment will be performed at first and last visit.
Treatment: Muscle power assessment, Muscle force assessment, Home-based mobility monitoring, Magnetic Resonance Imaging, and Gait assessment
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Analisi Della Perdita di Forza e Potenza Muscolare e Del Degrado Del Controllo Motorio Per la Predizione Delle Cadute in Una Popolazione Affetta da Artrosi di Ginocchio
- Fit questions
- Built from NCT06611618, who can take part
- Record updated
- 9 November 2026