Long-term safety of an eye injection for geographic atrophy from macular degeneration
Checks long-term safety of an eye injection, JNJ-81201887, in adults with geographic atrophy.
Plain-language title generated from the registry record
Registry title: A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)
Key facts
- Where
- Asheville, Austin, Baltimore, Beaufort, Boston, Carmel, Chevy Chase, Cincinnati, Cleveland, Dallas, Durham, Erie, Eugene, Fort Lauderdale, Fullerton, Gainesville, Grand Rapids, Hagerstown, Hickory, La Jolla, Lemont, Liverpool, Lynchburg, Marietta, Norfolk, Oxnard, Pasadena, Pensacola, Portland, Poway, Reno, Saint Louis Park, Salt Lake City, San Antonio, Spokane, Springfield, St Louis, St. Petersburg, The Woodlands, Tucson, Wake Forest, Walnut Creek, and Willow Park, United StatesSee the 45 sites
- Phase
- Phase 2/3
Where in United States
- Asheville Eye Associates - Western Carolina Retinal AssociatesAsheville, United StatesTaking people
- Austin Clinical ResearchAustin, United StatesTaking people
- Retina SpecialistsBaltimore, United StatesTaking people
- Charleston Neuroscience Institute, LLCBeaufort, United StatesTaking people
- Ophthalmic Consultants of BostonBoston, United StatesTaking people
- Midwest Eye InstituteCarmel, United StatesTaking people
- The Retina Group of WashingtonChevy Chase, United StatesTaking people
- Cincinnati Eye InstituteCincinnati, United StatesTaking people
- Cleveland Clinic - Main CampusCleveland, United StatesTaking people
- Texas Retina AssociatesDallas, United StatesTaking people
- UT Southwestern Medical CenterDallas, United StatesTaking people
- Duke Eye CenterDurham, United StatesTaking people
- Erie Retina ResearchErie, United StatesTaking people
- Verum Research, LLCEugene, United StatesTaking people
- Retina Group of FloridaFort Lauderdale, United StatesTaking people
- Retina Consultants of Orange CountyFullerton, United StatesTaking people
- VitreoRetinal Associates, PAGainesville, United StatesTaking people
- Foundation for Vision ResearchGrand Rapids, United StatesTaking people
- Cumberland Valley Retina ConsultantsHagerstown, United StatesTaking people
- Graystone EyeHickory, United StatesTaking people
- Shiley Eye Institute Jacobs Retina CenterLa Jolla, United StatesTaking people
- University RetinaLemont, United StatesTaking people
- Retina-Vitreous Surgeons of Central New YorkLiverpool, United StatesTaking people
- Piedmont Eye CenterLynchburg, United StatesTaking people
- Georgia RetinaMarietta, United StatesTaking people
- Marietta Eye ClinicMarietta, United StatesTaking people
- Wagner Kapoor Research InstituteNorfolk, United StatesTaking people
- California Retina ConsultantsOxnard, United StatesTaking people
- California Eye Medical SpecialistsPasadena, United StatesTaking people
- Retina Specialty InstitutePensacola, United StatesTaking people
- Maine Eye CenterPortland, United StatesTaking people
- Retina Consultants San DiegoPoway, United StatesTaking people
- Sierra Eye AssociatesReno, United StatesTaking people
- Retina Consultants of MinnesotaSaint Louis Park, United StatesTaking people
- University of UtahSalt Lake City, United StatesTaking people
- Retina Associates Of South Texas P ASan Antonio, United StatesTaking people
- Spokane Eye Clinical ResearchSpokane, United StatesTaking people
- Cascade Medical Research Institute, LLCSpringfield, United StatesTaking people
- The Retina InstituteSt Louis, United StatesTaking people
- Retina Vitreous Associates of FloridaSt. Petersburg, United StatesTaking people
- Retina Consultants of TexasThe Woodlands, United StatesTaking people
- Retina Associates Southwest PCTucson, United StatesTaking people
- NC Retina AssociatesWake Forest, United StatesTaking people
- Bay Area Retina AssociatesWalnut Creek, United StatesTaking people
- Strategic Clinical Research GroupWillow Park, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Janssen Research & Development, LLC
- Trial code
- NCT06635148EU 2022-500747-21-00
- Record updated
- 3 November 2026
- Original description
The purpose of this study is to assess the long-term safety and tolerability after an intravitreal injection (a shot of medicine into the eye) of JNJ-81201887 administered in parent clinical studies.Read full original descriptionShow less
Long-term Extension Study for Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD) in JNJ-81201887 Parent Clinical Studies
The purpose of this study is to assess the long-term safety and tolerability after an intravitreal injection (a shot of medicine into the eye) of JNJ-81201887 administered in parent clinical studies.
Inclusion: Participants who were enrolled and received treatment with JNJ-81201887 or sham in a parent clinical study (81201887MDG2001, 81201887MDG1003); Females (women of childbearing potential), male participants, and partners of male participants will not be required to use contraception in this LTE study; Must sign an informed consent form (ICF) indicating that participant understands the purpose of, and procedures required for, the study and is willing to participate in the study. The ICF may be signed by an impartial witness and/or legally designated representative depending on national/local regulations.
Exclusion: There are no exclusion criteria for this LTE study.