Treating Insomnia in Mild Cognitive Impairment
Key facts
- Where
- Boston, United StatesSee the site
Where in United States
- Beth Israel Deaconess Medical CenterBoston, United StatesContact: Alex Clinical Research CoordinatorTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Beth Israel Deaconess Medical Center
- Trial code
- NCT06687161
- Record updated
- 5 November 2026
- Original description
The goal of this study is to test a new way to improve sleep quality in persons living with mild cognitive impairment. The treatment combines a safe and gentle way to stimulate the brain, called transcranial magnetic stimulation, with a psychological treatment, called cognitive behavioral therapy for insomnia.Read full original descriptionShow less
Neuromodulation and Cognitive Behavioral Therapy for Insomnia in MCI
The goal of this study is to test a new way to improve sleep quality in persons living with mild cognitive impairment. The treatment combines a safe and gentle way to stimulate the brain, called transcranial magnetic stimulation, with a psychological treatment, called cognitive behavioral therapy for insomnia.
Inclusion: Aged 60 years or older; Speak and read English; Clinical diagnosis of MCI or Subjective Cognitive Impairment (SCI)-a perceived gradual worsening in cognitive ability relative to one's younger self, or peer group-reported by either the participant or informant; Reported insomnia symptoms (sleep-onset and/or sleep maintenance) that cause significant distress or impairment in social, occupational, or other areas of functioning over the past three months; Have access to an Internet-enabled computer or tablet at home, or ability to connect a BIDMC-provided tablet to the internet, with private space to complete cognitive testing; Capable of and willing to provide written informed consent.
Exclusion: Alcohol or drug abuse within the past year; Evidence of significant cognitive impairment or dementia; Uncontrolled moderate-to-severe obstructive sleep apnea or other untreated sleep disorder (e.g., Restless Leg Syndrome, Periodic Limb Movement Disorder, parasomnia). Sleep apnea that is managed (e.g., regular use of a CPAP) and stable for ≥3 months is allowed; Diagnosis of Parkinson's disease, Huntington's disease, Lewy-Body disease, or other neurological condition known to impact sleep; Current diagnosis of major psychiatric disorder (well-controlled depression or anxiety is permitted); Contraindications for TMS or MRI; Current psychological treatment for insomnia; Current opiate/opioid use; Irregular sleep schedule (bedtime before 8pm/after 2am OR wake time before 4am/after 10am), unless participant states they are willing and able to change if prompted.