Tests virtual reality physiotherapy in people with multiple sclerosis
Tests virtual reality added to physiotherapy in adults with moderate to severe multiple sclerosis.
Plain-language title generated from the registry record
Registry title: Impact of Virtual Reality Physiotherapy on Multiple Sclerosis Patients
Key facts
- Where
- Madrid and Móstoles, SpainSee the 2 sites
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with moderate to severe multiple sclerosis who can walk only with two supports. It tests virtual reality added to usual physiotherapy.
- Age
- 18 to 70 years
- Sex
- All sexes
- Disease stage
- Multiple sclerosis confirmed by McDonald criteria for more than two years, with an EDSS score of 6.5 or higher (needs two supports, such as two canes or a walker, to walk about 20 meters without resting).
- Earlier treatment
- Stable medical treatment for at least six months before the trial. No steroids, by vein or by mouth, in the 6 months before the assessment.
- Biomarker or test result
- A score of 24 or higher on the Minimental Test (no cognitive impairment, able to understand instructions).
Main reasons for not taking part
- Another neurological disease or musculoskeletal disorder besides multiple sclerosis
- Any heart, lung or metabolic disease, or other condition that may interfere with the study
- A relapse or hospital stay in the last 3 months
- Steroids in the last 6 months or during the trial
- Vision problems not corrected by glasses or lenses
Read by machine on 9 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 70 years old?
Source: NCT06735053, who can take part
Where in Spain
- Fundación Esclerosis Multiple Madrid (FEMM)Madrid, SpainTaking people
- Asociación Mostoleña de Esclerosis Múltiple (AMDEM)Móstoles, SpainTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- European University of Madrid
- Trial code
- NCT06735053
- Record updated
- 21 February 2025
- Original description
The goal of this clinical trial is to learn if virtual reality combined with conventional physiotherapy intervention works to treat moderate to severe multiple sclerosis persons. The main questions it aims to answer are:Read full original descriptionShow less
Experimental Study on the Impact of a Virtual Reality-Based Physiotherapy Program as a Complement to a Conventional Physiotherapy Program in Patients With Moderate to Severe Multiple Sclerosis
The goal of this clinical trial is to learn if virtual reality combined with conventional physiotherapy intervention works to treat moderate to severe multiple sclerosis persons. The main questions it aims to answer are:
* Does the application of a virtual reality-based program along with conventional physiotherapy produces improvements compared to the application of conventional physiotherapy and placebo virtual reality in motor aspects of patients with multiple sclerosis? * Does the application of a virtual reality-based program along with conventional physiotherapy produces improvements compared to the application of conventional physiotherapy and placebo virtual reality in cognitive aspects of patients with multiple sclerosis
Researchers will compare a virtual reality-based program along with conventional physiotherapy with a placebo virtual reality to see if virtual reality improve motor and cognitive aspects of multiple sclerosis.
Participants will:
* Visit the clinic twice a week for 10 weeks to receive a 1-hour session of virtual reality and conventional physiotherapy. * Be assessed using various scales and questionnaires at three different times: at the start of the study, at the end of the treatment, and 4 weeks after the study ends.
Inclusion: Confirmed diagnosis of Multiple Sclerosis based on McDonald criteria, with an evolution time of more than two years; All patients with Multiple Sclerosis are included according to the Kurtzke Multiple Sclerosis Disability Status Scale (EDSS) (ANNEX II) with a score greater than or equal to 6.5 (Need of two types of support to walk -two canes, walker...- about 20 meters without resting); Stable medical treatment for at least six months prior to intervention; Absence of cognitive impairment, with ability to understand instructions and to obtain a score equal to or greater than 24 on the Minimental Test.
Exclusion: To have suffered an exacerbation or hospitalization in the last 3 months before starting the assessment protocol, nor during the therapeutic intervention process; To have received a course of steroids, intravenously or orally, 6 months prior to the start of the assessment protocol and within the intervention period of the study duration; Diagnosis of another neurological disease or musculoskeletal disorder other than MS; Diagnosis of any cardiovascular, respiratory or metabolic disease, or other conditions that may interfere with this study; Visual disturbances not corrected by ocular devices.