Treating Toddler Obesity by Treating the Parent/Caregiver Obesity With Weight Loss Medications

Who can take part

• Self-identify as being of Hispanic/Latino or African American ethnicity
• BMI ≥30 with a stable weight (no more than 5% variation during the previous 3 months) and an agreement not to initiate any other weight loss
• HbAlc ≤ 6.4
• Fluent in written and spoken English
• Self-identify as being of Hispanic/Latino or African American ethnicity
• BMI ≥ 95th percentile for age, gender and height
• Age 12 to 36 months of age
• Spends at least half of its awake time per day with the P/OCG who is the consenting adult and who provides at least half of the toddler's diet on that day

Who cannot take part

• Have been treated with prescription drugs that promote weight loss (for example, liraglutide [Saxenda™], orlistat [Xenical®], phentermine Adipex®], phentermine/topiramate [Qsymia™], semaglutide 2.4 mg [Wegovy™], tirzepatide [Zepbound™], bupropion/naltrexone [Contrave™], phentermine [Lomaira™] or similar other weight loss medications including over-the-counter (OTC) medications (for example, Alli®). Use of obesogenic medications (including but not limited to steroids, haloperidol, clozapine, risperidone, olanzapine, amitriptyline, imipramine, paroxetine, and lithium) which cannot be substituted or stopped
• Use of obesogenic medications (including but not limited to steroids, haloperidol, clozapine, risperidone, olanzapine, amitriptyline, imipramine, paroxetine, and lithium) which cannot be substituted or stopped
• Current cancer treatment
• History of drug or alcohol abuse
• Current cancer treatment
• Genetic disorders and/or physical or mental handicaps that would limit participation in the study and/or the lifestyle intervention
• Unwilling to use accepted standards of birth control if female and before menopause age. (i.e. IUD, birth control pills/injections, tubal or vas deferens ligation) during the study and for 30 days after the study is completed. Condoms or rhythm methods are not sufficient
• Nursing or planning to become pregnant in the next 10 months
• Any special dietary or exercise requirements
• Any established chromosome abnormalities that might be associated with obesity