Structured care approach for older people with atrial fibrillation and other conditions
Tests a structured care program in older people with atrial fibrillation and several health conditions.
Plain-language title generated from the registry record
Registry title: Integrated Approach in Frail Older People with Atrial Fibrillation
Key facts
- Where
- Alicante, Cartagena, Cártama, Elche, Málaga, Murcia, Sant Joan d'Alacant, Tarragona, and Valls, SpainSee the 10 sites
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for outpatients aged 65 or older with atrial fibrillation and at least one other long-term illness. It tests a structured team approach to care.
- Age
- 65 years or older
- Sex
- All sexes
- Disease stage
- Atrial fibrillation (first diagnosed, paroxysmal, persistent, long-standing persistent or permanent), confirmed by ECG or Holter monitoring, plus at least 1 other long-term illness
Main reasons for not taking part
- Mechanical prosthetic heart valve or moderate/severe mitral stenosis
- Serious disease with life expectancy under 12 months
- Unable to understand the study or attend follow-up
- Taking part in other interventional studies
- Unwilling to sign written informed consent
Read by machine on 9 November 2026.
Where in Spain
- Hospital General Universitario de Alicante Doctor Balmis-CARDIOLOGYAlicante, SpainContact: AMAYA GARCÍA-FERNÁNDEZ, MDTaking people
- Hospital General Universitario Santa Lucía-CARDIOLOGYCartagena, SpainContact: IGNACIO GIL-ORTEGA, MDTaking people
- Hospital Valle del Guadalhorce-CARDIOLOGYCártama, SpainContact: JORGE RODRÍGUEZ CAPITÁN, MDTaking people
- Hospital General Universitario de Elche-CARDIOLOGYElche, SpainContact: ANTONIO GARCÍA-HONRUBIA, MDTaking people
- Hospital Universitario Virgen de la Victoria-CARDIOLOGYMálaga, SpainContact: ALEJANDRO ISIDORO PÉREZ CABEZA, MDTaking people
- Hospital Clínico Universitario Virgen de la Arrixaca-CARDIOLOGÍAMurcia, SpainContact: FRANCISCO MARIN, MDTaking people
- Hospital General Universitario Reina Sofía-CARDIOLOGYMurcia, SpainContact: TOMÁS VICENTE VERA, MDTaking people
- Hospital Universitario San Juan de Alicante-CARDIOLOGYSant Joan d'Alacant, SpainContact: JOSE MORENO ARRIBAS, MDTaking people
- Hospital Universitario de Tarragona Joan XXIII-CardiologyTarragona, SpainContact: JOSÉ LUÍS FERREIRO-GUTIÉRREZ, MDTaking people
- Pius Hospital de Valls-CardiologyValls, SpainContact: LEYDIMAR ADEL ANMAD SHIHADEH MUSA, MDTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Heart Care Foundation
- Trial code
- NCT06775028
- Record updated
- 14 January 2025
- Original description
The study will verify if a structured multidisciplinary approach (called iABC), aimed to improve the appropriate management of elderly AF patients with multimorbidity (the i-ABC group), would provide a clear evidence of an improvement in clinical conditions and quality of life compared to usual clinical care. The i-ABC group in AFFIRMO will follow the ABC pathway, focused on three domains: avoid stroke with anticoagulation (with optimized VKA or label-adherent DOAC use); better symptom management; and optimized management of associated cardiovascular and non cardiovascular comorbidities.Read full original descriptionShow less
AFFIRMO - Atrial Fibrillation Integrated Approach in Frail, Multimorbid and Polymedicated Older People
The study will verify if a structured multidisciplinary approach (called iABC), aimed to improve the appropriate management of elderly AF patients with multimorbidity (the i-ABC group), would provide a clear evidence of an improvement in clinical conditions and quality of life compared to usual clinical care. The i-ABC group in AFFIRMO will follow the ABC pathway, focused on three domains: avoid stroke with anticoagulation (with optimized VKA or label-adherent DOAC use); better symptom management; and optimized management of associated cardiovascular and non cardiovascular comorbidities.
The study will be conducted in Bulgaria, Denmark, Italy, Romania, Serbia and Spain .
Inclusion: Outpatients of both sexes with age ≥65 years; First diagnosed, paroxysmal, persistent, long-standing persistent or permanent AF, confirmed as per guideline-recommended diagnostic criteria for AF, e.g. with electrocardiogram (ECG) or Holter monitoring; ≥1 additional long-term comorbidity, thus fulfilling the definition of multimorbidity: hypertension (treated with at least 2 antihypertensive drugs), coronary artery disease (CAD), peripheral artery disease, heart failure, stroke/TIA, diabetes mellitus, COPD, CKD.
Exclusion: Mechanical prosthetic heart valve or moderate/severe mitral stenosis; Serious diseases with a life expectancy inferior to 12 months; Patient unwilling to be enrolled and sign written informed consent; Patient unable to understand the study and attend the follow-up; Patients included in other interventional studies; Only for sites randomized to the iABC group:; Patient without a device suitable for iABC use.