Catheter Ablation Compared With Medicines in Atrial Fibrillation After Stroke
Tests early catheter ablation against routine medicines in adults with atrial fibrillation and recent stroke.
Plain-language title generated from the registry record
Registry title: Assessing the Neurological Outcomes After Atrial Fibrillation Ablation for Rhythm Control
Key facts
- Where
- Independence, Kansas City, and Overland Park, United StatesSee the 7 sites
Where in United States
- Centerpoint Medical CenterIndependence, United StatesNo longer taking part
- Centerpoint Medical Center ClinicIndependence, United StatesNo longer taking part
- Research Medical CenterKansas City, United StatesNo longer taking part
- Research Medical Center ClinicKansas City, United StatesNo longer taking part
- Kansas City Heart Rhythm Institute - Roe ClinicOverland Park, United StatesNo longer taking part
- Menorah Medical CenterOverland Park, United StatesNo longer taking part
- Overland Park Regional Medical CenterOverland Park, United StatesNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Kansas City Heart Rhythm Research Foundation
- Trial code
- NCT06783868
- Record updated
- 28 August 2025
- Original description
A prospective, non-blinded, multi-center study to assess the impact of early Catheter Ablation (CA) in patients with a new diagnosis of Atrial Fibrillation(AF) at the time of stroke. 100 patients will be enrolled.Read full original descriptionShow less
Randomized Control Study to Assess the Neurological Outcomes After Atrial Fibrillation Ablation for Rhythm Control vs Routine Medication Therapy in Patients With Recent Stroke: SAVE STROKE Phase II Study
A prospective, non-blinded, multi-center study to assess the impact of early Catheter Ablation (CA) in patients with a new diagnosis of Atrial Fibrillation(AF) at the time of stroke. 100 patients will be enrolled.
Inclusion: Ages >18 and able to provide consent; Presenting with an acute stroke and new-onset AF; Modified RANKIN score (mRS) < 6; Must be able to undergo some form of cardiac monitoring [implantable loop recorder (ILR), electrocardiogram (ECG), Holter monitor] to quantify AF burden.
Exclusion: Patients < 18 years of age; Unable to provide consent, including mRS = 6; Not able to read and write at an 8th-grade level [to complete AFEQT and EQ-5D surveys]; Positive B-hCG; Will not follow up with our practice/clinic afterward; Cannot tolerate OAC or AAD for any reason; Cannot undergo CA for any reason.