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Studies pain and sex hormones in endometriosis and migraine

Compares pain sensitivity and hormone levels in people with endometriosis, migraine, or both.

Plain-language title generated from the registry record
Registry title: Endometriosis and Migraine

Key facts

Where
St Louis, United StatesSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 12 and 45 years old?

Source: NCT06785129, who can take part

Where in United States

  • Washington University School of MedicineSt Louis, United StatesTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Washington University School of Medicine
Trial code
NCT06785129
Record updated
13 July 2026
Original description
This study aims to determine differences in experimental pain and sex hormone levels between patients with migraine, patients with endometriosis, patients with migraine and endometriosis, and healthy controls. Participants will complete surveys, experimental pain paradigms and collection of samples for hormone analyses.Read full original descriptionShow less

Mechanisms Underlying Endometriosis and Migraine Comorbidity

This study aims to determine differences in experimental pain and sex hormone levels between patients with migraine, patients with endometriosis, patients with migraine and endometriosis, and healthy controls. Participants will complete surveys, experimental pain paradigms and collection of samples for hormone analyses.

Inclusion: Patients with diagnosed endometriosis, migraine, or both endometriosis and migraine; Healthy control subjects with no history of chronic pain; Age 12-45; Assigned female sex at birth.

Exclusion: Current use of dopamine agonist or SSRI medications; Presence of psychiatric, neurological, endocrinological and/or developmental conditions and taking medications for these conditions; For patients aged 12-17 not having a parent/legal guardian willing to sign the consent and answer surveys about their child's health; Pregnancy or breastfeeding; Presence of prolactinoma.

ClinicalTrials.gov NCT06785129