Early access
Sign in
Taking people in United StatesPhase 4

Platelet-rich plasma compared with steroid injections for hip osteoarthritis pain

Compares platelet-rich plasma and corticosteroid injections for pain and function in hip osteoarthritis.

Key facts

Who runs it
LifeBridge Health
Where
Baltimore, United StatesSee the site
Trial code
Registry title
Platelet Rich Plasma Versus Corticosteroids in Hip Osteoarthritis Pain
Status
Recruiting
Phase
Phase 4
People taking part
54 people, planned
Started
21 Feb 2024
Planned end
1 Dec 2025
Type of study
Interventional, 2 groupsOne group gets an existing treatment, for comparison.
Treatments tested
  • Platelet Rich Plasma Joint Injection
  • Corticosteroid Injection
Record updated
14 March 2025

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with hip osteoarthritis pain who need a hip injection. It compares platelet rich plasma (PRP) injections with corticosteroid injections.

Age
21 to 80 years
Sex
Men and women can join.
Disease stage
Hip osteoarthritis of Kellgren-Lawrence (KL) grade II or III on X-ray, where a hip injection is planned to treat symptoms.
Earlier treatment
No injections into the hip being studied within the last three months.

Main reasons for not taking part

  • Current skin infection over the hip
  • Current or past diagnosis of "chronic pain", or being opioid tolerant (for example at least 60 mg of morphine daily for a week or longer)
  • Diabetes Mellitus
  • Allergy to any ingredient or medicine used in either group
  • Pregnant, or planning to be pregnant within the following 3 months or during the study

The registry criteria, word for word

Show all 14 criteriaShow less

Who can take part

  • Provision of signed and dated informed consent form
  • Stated willingness to comply with all study procedures and availability for the duration of the study
  • Male or female, aged 21-80 years
  • Radiographic diagnosis of Kellgren-Lawrence (KL) grade of II or III Hip osteoarthritis
  • Indicated for a Hip injection to treat Hip OA symptoms

Who cannot take part

  • Current or previous diagnosis of "chronic pain"
  • Treatment with another investigational drug or other intervention for pain
  • Current overlying skin infection
  • Allergy to any potential ingredients or medications utilized in any of the two groups
  • Diagnosis of Diabetes Mellitus
  • Any condition(s) or diagnosis, both physical or psychological, or physical exam finding in the opinion of the investigator that would precludes participation
  • Any injections into the target Hip within three months
  • Opioid tolerant at time of screening (for a week or longer, at least 60 mg of morphine daily, or at least 30 mg of oral oxycodone daily, or at least 8 mg of oral hydromorphone daily or an equianalgesic dose of another opioid.)
  • If female, pregnant or planning to be pregnant within the following 3 months or study duration

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 21 and 80 years old?

Where in United States

  • Sinai Hospital of BaltimoreBaltimore, United StatesContact: Martin Gesheff, DHScTaking people

About the trial

What the trial wants to find out

Prospective, single-center that may go on to being multicenter, randomized trial comparing platelet rich plasma (PRP) versus corticosteroid injection for the treatment of symptoms of Hip osteoarthritis. The purpose of the study is to determine which therapy provides a greater reduction in patient reported outcome measures of pain and function.

The 2 groups in the trial

  • Autologous Platelet Rich PlasmaTreatment being tested

    \~Injection of approximately 10 mL autologous PRP Magellan Autologous Concentration System, ISTO Biologics

    Treatment: Platelet Rich Plasma Joint Injection

  • CorticosteroidExisting treatment, for comparison

    5 milliliters (mL) injection of corticosteroid (1cc Kenalog, 4cc Xylocaine) Kenalog - 40 (triamcinolone acetonide injectable suspension, USP) Xylocaine - MPF (lidocaine HCl Injection, USP)

    Treatment: Corticosteroid Injection

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
The Efficacy of Platelet Rich Plasma Compared With Corticosteroid Injections for the Treatment of Pain Associated With Hip Osteoarthritis
Plain-language title
Platelet-rich plasma compared with steroid injections for hip osteoarthritis painGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 14 November 2026.
Fit questions
Built from NCT06793982, who can take part
Record updated
14 March 2025