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Studies how talking with caregivers affects speech in people with ALS

Tests how conversation with caregivers affects speech in adults with amyotrophic lateral sclerosis.

Plain-language title generated from the registry record
Registry title: Examining Interactions Between PALS and Caregivers

Key facts

Where
University Park, United StatesSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 90 years old?

Source: NCT06819124, who can take part

Where in United States

  • Speech Core, Pennsylvania State UniversityUniversity Park, United StatesTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Penn State University
Trial code
NCT06819124
Record updated
6 April 2026
Original description
The goal of this clinical trial is to learn about the effect of communicative interaction on verbal communication in people with amyotrophic lateral sclerosis (ALS) and their caregivers.Read full original descriptionShow less

Examining Interactions Between Persons With ALS and Caregivers

The goal of this clinical trial is to learn about the effect of communicative interaction on verbal communication in people with amyotrophic lateral sclerosis (ALS) and their caregivers.

The question is, What are the effects of communicative interaction on verbal communication in people with ALS when they interact with their caregivers and does this change over time?

Participants will read words and sentences while they are interacting with their caregivers.

Inclusion: Speakers with amyotrophic lateral sclerosis (ALS) (PALS-people with ALS); diagnosis of ALS following the revised EL Escorial criteria; no history of other neurological conditions (e.g., stroke); no cognitive impairment assessed by Telephone Montreal Cognitive Assessment (mini MoCA); detectable speech disturbance according to the ALS Functional Rating Scale-Revised (ALSFRS-R); the ability to produce single words; being a native speaker of American English (AE); Caregivers; being a caregiver of a participant with ALS; being a native speaker of American English (AE).

Exclusion: None - if volunteer meets the inclusion criteria, then they will be enrolled.

ClinicalTrials.gov NCT06819124