Studies immune and virus markers in adults with HPV-linked throat cancer
Collects tumor tissue and blood from adults with HPV-linked throat cancer.
Plain-language title generated from the registry record
Registry title: Patients With Human Papillomavirus-associated Head and Neck Cancer for the Discovery of Predictive Biomarkers to Guide Clinical Intervention
Key facts
- Where
- Rome, ItalySee the site
Where in Italy
- IRCCS National Cancer Institute "Regina Elena"Rome, ItalyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Regina Elena Cancer Institute
- Trial code
- NCT06821243
- Record updated
- 5 June 2026
- Original description
Prospective pilot study, non-interventional, of a biological/radiological nature, which involves the collection of tissue samples, and blood from patients suffering from squamous cell carcinoma of the oropharynx OPSCC for detection of HPV-DNA/RNA and immuno-phenotypic analysis of T cells, study of extracellular vesicles, and dosages of cytokines and chemokines involved in the immune responseRead full original descriptionShow less
Multidimensional Assessment of Virus-associated Head and Neck Cancer Patients for the Discovery of Predictive Biomarkers to Guide Clinical Intervention
Prospective pilot study, non-interventional, of a biological/radiological nature, which involves the collection of tissue samples, and blood from patients suffering from squamous cell carcinoma of the oropharynx OPSCC for detection of HPV-DNA/RNA and immuno-phenotypic analysis of T cells, study of extracellular vesicles, and dosages of cytokines and chemokines involved in the immune response
Inclusion: Squamous cell carcinomas of the oropharynx (OPSCC) candidates for surgical; Age > 18 years; ECOG performance status <_ 2; Signature of informed consent (to participate in the study and data processing).
Exclusion: Previous head and neck cancer; Presence of distant metastases at the time of diagnosis.