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Studies how infants of depressed mothers respond to facial emotions

Tests infant attention to emotional faces in babies whose mothers have postpartum depression.

Plain-language title generated from the registry record
Registry title: Development of Attentional Biases for Affective Cues in Infants of Mothers With Depression

Key facts

Where
Binghamton, United StatesSee the site

Where in United States

  • Binghamton UniversityBinghamton, United StatesTaking people

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Trial details

Who runs it
Binghamton University
Trial code
NCT06835855
Record updated
30 September 2026
Original description
The goal of this study is to examine attentional biases for facial displays of emotion as a mechanism of risk in infants of mothers with postpartum major depression, and the potential role of infant arousal in the development of these attentional biases.Read full original descriptionShow less

Development of Attentional Biases for Affective Cues in Infants of Mothers With Depression

The goal of this study is to examine attentional biases for facial displays of emotion as a mechanism of risk in infants of mothers with postpartum major depression, and the potential role of infant arousal in the development of these attentional biases.

Inclusion: The high-risk group (n = 150) will consist of women with at least one episode of MDD since their baby's birth; To qualify for the low-risk group (n = 75), women cannot have a history of any depressive disorder or any current psychiatric diagnoses; Infants will be required to be singleton children born full-term (> 37 weeks) and normal weight (> 2,500 grams) with no birth complications or health problems to avoid medical complications contributing to infants' attention, reactivity, and regulation measures; The two groups will be matched on demographic factors (e.g., age, race/ethnicity, income).

Exclusion: Additional exclusion criteria are diagnoses of alcohol or substance use disorders currently or at any point during pregnancy, or lifetime history of bipolar or psychotic disorders.

ClinicalTrials.gov NCT06835855