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Virtual reality memory training for older adults with mild cognitive impairment

Tests virtual reality thinking-skills therapy in older people with mild cognitive impairment.

Key facts

Who runs it
The Hong Kong Polytechnic University
Where
Hong Kong1 site in 1 countryChoose a country to see its sites
Trial code
Registry title
Using Immersive Virtual Reality for Cognitive Therapy in Elderly with Mild Cognitive Impairment
Status
Not yet recruiting
People taking part
66 people, planned
Started
3 Jul 2025
Expected to end
30 Apr 2027
Type of study
Interventional, 2 groupsOne group gets an existing treatment, for comparison.
Treatments tested
  • IVR-CST (Immersive Virtual Reality Cognitive Stimulation Therapy)
  • Intervention Name: Conventional CST (Cognitive Stimulation Therapy)
Record updated
20 February 2025

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for people aged 60 or older with mild cognitive impairment (MCI), a mild decline in memory or thinking. It compares cognitive stimulation therapy using virtual reality with the usual version.

Age
60 Years or older
Sex
All
Disease stage
Mild cognitive impairment diagnosed by a psychiatrist, or a score of 16-21 out of 30 on the Hong Kong Brief Cognitive Test (HKBC).
Earlier treatment
People who have had CST (cognitive stimulation therapy) before cannot join. People taking medicine for MCI or dementia, such as aducanumab, cannot join.

Main reasons for not taking part

  • Dementia, or another mental or brain illness such as depression, stroke, brain injury or Parkinson's disease
  • Nausea, headache or other strong discomfort during the 10-minute virtual reality test
  • Hearing, vision or arm problems that make taking part hard
  • Taking part in another clinical therapy trial at the same time
  • Prior CST treatment or use of medicine for MCI or dementia

The registry criteria, word for word

Show all 11 criteriaShow less

Who can take part

  • elderly aged 60 years or above,
  • a diagnosis of MCI made by a psychiatrist, or a score of 16-21 out of 30 in the Hong Kong Brief Cognitive Test (HKBC, 31), with upper and lower cutoff scores for MCI as suggested by the test. HKBC has been validated in Hong Kong with satisfactory sensitivity (0.88) and specificity ((0.81) in differentiating subjects with MCI and healthy individuals,
  • ability to speak and comprehend Cantonese,
  • normal or corrected-to-normal binocular vision and hearing,
  • absence of physical illness/disability to prevent them from IVR-CST participation, 6, compatible with IVR exposure in the 10-minute IVR trial without major signs of cybersickness, based on the symptoms given in the Simulator Sickness Questionnaire

Who cannot take part

  • concurrent participation in other clinical therapy trials,
  • prior CST treatment,
  • a diagnosis of dementia or other psychiatric/neurological diseases such as depression, stroke, brain trauma, Parkinson's disease
  • Use of medication for MCI/dementia, e.g., aducanumab
  • incompatibility with IVR exposure such as complaints of nausea, headache, or other severe discomforts during trial use,
  • hearing/visual/upper limb impairments that hinder CST/IVR-CST participation,

This trial has no sites in United States.

It has sites in one country. Choose a country to see its sites.

About the trial

What the trial wants to find out

The proposed study aims to investigate the potential of IVR-CST in improving cognition of people with MCI, and as well the association of eye movement during therapy and treatment outcomes of IVR-CST. Four research questions have been proposed and listed as follows:

Read full original descriptionShow less

1. Is IVR-CST a feasible treatment for elderly with MCI? 2. Is IVR-CST an efficacious treatment for improving cognition of elderly with MCI? 3. Is IVR-CST more efficacious than conventional CST (i.e., without IVR) in improving the cognition of elderly with MCI? 4. Is eye-tracking data collected during therapy associated with treatment outcomes of IVR CST?

The 2 groups in the trial

  • IVR-CST GroupTreatment being tested

    Treatment: IVR-CST (Immersive Virtual Reality Cognitive Stimulation Therapy)

  • Conventional CST GroupExisting treatment, for comparison

    Treatment: Intervention Name: Conventional CST (Cognitive Stimulation Therapy)

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Utilization of Immersive Virtual Reality in Cognitive Stimulation Therapy (IVR-CST) for Elderly with Mild Cognitive Impairment: a Randomized Controlled Pilot Study
Plain-language title
Virtual reality memory training for older adults with mild cognitive impairmentGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 15 November 2026.
Publications
Record updated
20 February 2025