Brain and Behavior Study of Obesity in Children Ages 7 to 12
Studies brain activity and eating behavior in children with obesity or overweight.
Key facts
- Who runs it
- Johns Hopkins University
- Where
- Baltimore, Providence, and Seattle, United StatesSee the 4 sites
- Trial code
- Registry title
- Brain and Behavior Influences on Obesity Development From Infancy Through Childhood
- Status
- Recruiting
- People taking part
- 210 people, planned
- Started
- 2 Dec 2024
- Expected to end
- 31 Mar 2029
- Type of study
- Interventional
- Treatments tested
- fMRI cue reactivity task
- fMRI go no go task
- Ad libitum meal test
- Eating in the absence of hunger test
- Record updated
- 7 May 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for children from the RESONANCE study who reach 7-12 years of age during the project and have no food allergies.
- Age
- 7 to 12 years
- Sex
- All sexes can join.
Main reasons for not taking part
- Food allergies
- Alcohol, cigarette or illicit substance exposure before birth
- Problems seen on the first-trimester fetal ultrasound
- Complicated pregnancy or delivery, including APGAR score less than 8 or NICU admission
- Neurological, psychiatric or developmental disorder, or a reason not to have an MRI scan (such as metal in the body or claustrophobia)
The registry criteria, word for word
Show all 2 criteriaShow less
Who can take part
- Participants from the RESONANCE cohort are eligible if the participant will reach 7-12 years of age during the proposed project period and have no food allergies
Who cannot take part
- Exclusion criteria for RESONANCE include:; In utero exposure to alcohol, cigarette, or illicit substances; First trimester fetal US abnormalities; Complicated pregnancy (e.g., pre-eclampsia); Complicated delivery, including APGAR scores less than 8 and/or neonatal intensive care unit (NICU) admission; History of neurological (e.g., epilepsy), psychiatric (e.g., anxiety or depression requiring treatment with medication) or developmental disorder (e.g., autism spectrum disorder (ASD), dyslexia); Contraindications for MRI including metal in the body, claustrophobia
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 7 and 12 years old?
Where in United States
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.Baltimore, United StatesContact: Susan Carnell, PhDNo longer taking part
- Johns Hopkins University School Of MedicineBaltimore, United StatesContact: Susan Carnell, PhDNo longer taking part
- Rhode Island HospitalProvidence, United StatesContact: Viren D'Sa, MDTaking people
- University of WashingtonSeattle, United StatesContact: Susan Carnell, PhDNo longer taking part
About the trial
What the trial wants to find out
The investigators project, RESONATE, aims to investigate why some children develop obesity. To do this it uses data on eating and eating-related behaviors, genetic and environmental factors, and brain structure and function. This data is collected in a sub-sample of RESONANCE, a large study of families of children from infancy through childhood. The results will lay foundations for the development of early interventions to prevent or treat obesity.
The group in the trial
- Single armOther group
Treatment: fMRI cue reactivity task, fMRI go no go task, Ad libitum meal test, and Eating in the absence of hunger test
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Early Brain Development and Child Nutrition and Obesity
- Plain-language title
- Brain and Behavior Study of Obesity in Children Ages 7 to 12Generated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Fit questions
- Built from NCT06861868, who can take part
- Record updated
- 7 May 2026