Tests the Mayo Clinic Diet for weight loss in adults with obesity
Compares the Mayo Clinic Diet with usual care in adults with obesity.
Plain-language title generated from the registry record
Registry title: Weight Loss Through Mayo Clinic Diet
Key facts
- Where
- Rochester, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 64 years old?
Source: NCT06862375, who can take part
Where in United States
- Mayo Clinic in RochesterRochester, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Mayo Clinic
- Trial code
- NCT06862375
- Record updated
- 21 October 2026
- Original description
The purpose of study is to evaluate the efficacy of the Mayo Clinic Diet in clinically significant weight loss (>5%) versus usual care. We also wish to evaluate the feasibility, barriers to completion, and sustainability of this intervention at the 24, and 52-week marks. Lastly, we aim to study the change in participants body composition and quality of life at the end of this intervention.Read full original descriptionShow less
Weight Loss Through Mayo Clinic Diet; a Prospective Pilot Study
The purpose of study is to evaluate the efficacy of the Mayo Clinic Diet in clinically significant weight loss (>5%) versus usual care. We also wish to evaluate the feasibility, barriers to completion, and sustainability of this intervention at the 24, and 52-week marks. Lastly, we aim to study the change in participants body composition and quality of life at the end of this intervention.
Inclusion: Males and females (non-pregnant) 18-64; BMI > or = to 25 kg/m2; Ability to read and understand English. (as the Mayo Clinic Diet book and app are only available in English).
Exclusion: Had weight loss surgery within the last year; Currently participating in another lifestyle weight loss program or taking medications for weight loss; Have planned surgery in the next 6 months; Have a current diagnosis of melanoma or cancer diagnosis; Have a diagnosis of Type 1 or 2 Diabetes Mellitus; Have a history of eating disorders; Currently breastfeeding; Pregnant, or planned to be pregnant within 6 months; Have lost 5% or more of their weight in the last six months.