Screening for long-term lung blood clot complications after a pulmonary embolism
Tests a screening program for chronic lung blood clot disease in adults after pulmonary embolism.
Plain-language title generated from the registry record
Registry title: Early Detection of CTEPH in Patients After APE
Key facts
- Where
- Brno, Havlíčkův Brod, Hradec Králové, Jihlava, Náchod, Olomouc, Ostrava, Pardubice, Rychnov nad Kněžnou, and Tábor, CzechiaSee the 10 sites
Where in Czechia
- Brno University HospitalBrno, CzechiaTaking people
- Havlíčkův Brod HospitalHavlíčkův Brod, CzechiaTaking people
- University Hospital Hradec KraloveHradec Králové, CzechiaTaking people
- Jihlava HospitalJihlava, CzechiaTaking people
- Náchod HospitalNáchod, CzechiaTaking people
- University Hospital OlomoucOlomouc, CzechiaTaking people
- University Hospital OstravaOstrava, CzechiaTaking people
- Pardubice HospitalPardubice, CzechiaTaking people
- Rychnov nad Kněžnou HospitalRychnov nad Kněžnou, CzechiaTaking people
- Tábor HospitalTábor, CzechiaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Institute of Health Information and Statistics of the Czech Republic
- Trial code
- NCT06865326
- Record updated
- 4 November 2026
- Original description
The project is a national, prospective, multicenter, observational pilot project of screening CTEPH in pacients after APE in the Czech Republic. The main goal of the project is to methodically prepare, implement and evaluate a pilot project that will verify the suitability of the proposed procedure of early detection of Chronic tromboembolic pulmonary hypertesion in such a way as to ensure the maximum positive impact on the health of the population and high cost-effectiveness of the whole process.Read full original descriptionShow less
Early Detection of Chronic Thromboembolic Pulmonary Hypertension in Patients After Acute Pulmonary Embolism
The project is a national, prospective, multicenter, observational pilot project of screening CTEPH in pacients after APE in the Czech Republic. The main goal of the project is to methodically prepare, implement and evaluate a pilot project that will verify the suitability of the proposed procedure of early detection of Chronic tromboembolic pulmonary hypertesion in such a way as to ensure the maximum positive impact on the health of the population and high cost-effectiveness of the whole process.
Inclusion: Age over 18 years; Signed consent to participate in the project and GDPR; Patients with an episode of acute pulmonary embolism in the last 3-12 months, with ongoing anticoagulation therapy:; Patients with new-onset and ongoing or progressive dyspnea (min. NYHA II) after a pulmonary embolism episode or worsening of dyspnea after a pulmonary embolism episode compared to the status before the episode (at least 1 HYHA grade) or; Asymptomatic patients after a pulmonary embolism episode and at least one of the following risk factors:; ECHO evidence of severe PH at diagnosis of PE (PASP >60 mmHg); Antiphospholipid syndrome with triple positivity (presence of lupus anticoagulans + anti-beta-2-glycoprotein I (B2GPI) antibodies + anticardiolipin); Infected permanent venous inlets and cardiac pacing/defibrillation intravascular systems; Presence of ventriculoatrial shunt for treatment of hydrocephalus; Nonspecific intestinal inflammation (ulcerative colitis, Crohn's disease); History of splenectomy; Myeloproliferative disorders; Chronic osteomyelitis.
Exclusion: Not agreeing to participate in the project; Contraindications to treatment.