Robotic rehabilitation for people treated for soft tissue sarcoma
Tests robotic rehabilitation in adults treated for localized soft tissue sarcoma.
Plain-language title generated from the registry record
Registry title: Soft Tissue Sarcoma: Motor Performance, Robotic Rehabilitation, Nutrition, and Quality of Life
Key facts
- Where
- Naples, Roma, and Rome, ItalySee the 3 sites
Where in Italy
- Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale"Naples, ItalyNot yet recruiting
- Fondazione Don Carlo Gnocchi ONLUSRoma, ItalyNo longer taking part
- Fondazione Policlinico Universitario Campus Bio-MedicoRome, ItalyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Fondazione Policlinico Universitario Campus Bio-Medico
- Trial code
- NCT06873685
- Record updated
- 21 March 2025
- Original description
Soft tissue sarcomas are a group of rare and heterogeneous tumors. Surgery is the mainstay of treatment and microscopic negative margins need to be achieved to improve disease local control. We designed this prospective study to evaluate the main features of motor impairment and the impact of tailored robotic rehabilitation techniques in patients treated for localized soft tissue sarcoma (surgery alone, or surgery + radiation or radiochemotherapy). Specific patients' motor strategies will be quantitatively measured through a biomechanical assessment, including the analysis of joint kinematics, and muscle activity timing patterns. Considering the influence of motor impairment after demolitive surgery, a major interest of this study will be focused on nutrition and Quality of life which will be prospectively evaluated by specific questionnaires at different time points.Read full original descriptionShow less
Soft Tissue Sarcoma: Instrumented Evaluation of Motor Performance and Impact of Robotic Rehabilitation, Nutrition and Quality of Life Assessment (START-RUN1)
Soft tissue sarcomas are a group of rare and heterogeneous tumors. Surgery is the mainstay of treatment and microscopic negative margins need to be achieved to improve disease local control. We designed this prospective study to evaluate the main features of motor impairment and the impact of tailored robotic rehabilitation techniques in patients treated for localized soft tissue sarcoma (surgery alone, or surgery + radiation or radiochemotherapy). Specific patients' motor strategies will be quantitatively measured through a biomechanical assessment, including the analysis of joint kinematics, and muscle activity timing patterns. Considering the influence of motor impairment after demolitive surgery, a major interest of this study will be focused on nutrition and Quality of life which will be prospectively evaluated by specific questionnaires at different time points.
Inclusion: patient with primary and localized STS who is a candidate for limb-sparing surgery or retroperitoneal multivisceral resection (including partial or complete resection of the iliopsoas muscle with functional loss and potential femoral nerve involvement) with curative intent; age 18 years or older.
Exclusion: candidate for palliative and non-radical surgery; metastatic disease; recurrent tumors; refusal to sign informed consent; Pregnant or breastfeeding women at the time of screening.