Tests different electrical brain stimulation methods in people with dementia
Compares several brain stimulation types, paired with cognitive exercises, in adults with dementia.
Plain-language title generated from the registry record
Registry title: Longitudinal Study to Investigate Different Transcranial Electrical Stimulation
Key facts
- Where
- Winnipeg, CanadaSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for people aged 50 to 95 with dementia who read, write and speak English fluently. They try several types of brain stimulation with thinking exercises.
- Age
- 50 Years to 95 Years
- Sex
- All sexes can join.
- Disease stage
- Dementia, with a MoCA score between 5 and 24.
- Earlier treatment
- Must not plan to change medication during any treatment period (5 weeks including the pre-post assessments). Must not be in another dementia treatment study.
Main reasons for not taking part
- Parkinson's disease, Parkinsonian dementia, Huntington disease, significant aphasia, intellectual disability, or a major mood disorder such as major depression, bipolar disorder or schizophrenia
- History of epileptic seizures or epilepsy
- Vision or hearing problems severe enough to affect the thinking tests
- Current substance abuse disorder
- Cannot communicate well in English
Read by machine on 9 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 50 and 95 years old?
Source: NCT06877312, who can take part
Where in Canada
- Riverview Health CentreWinnipeg, CanadaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- University of Manitoba
- Trial code
- NCT06877312
- Record updated
- 4 December 2025
- Original description
This research investigates the effect of different frequencies of tACS (0 Hz, 30 Hz, 50 Hz, 70 Hz, 90 Hz) and tRNS with cognitive exercises in a regimen protocol of 4 weeks, everyday (Monday to Friday). The study design is a longitudinal study design in which participants receive different tES randomly ordered. Treatments occur for 4 weeks, then 12 weeks of no treatment (wash-out period), repeated for each tES treatment type. Participants have the option of having their choice of music in the background while they perform cognitive exercises.Read full original descriptionShow less
Longitudinal Study to Investigate Different Treatment Protocols of Transcranial Electrical Stimulation for Individuals With Dementia
This research investigates the effect of different frequencies of tACS (0 Hz, 30 Hz, 50 Hz, 70 Hz, 90 Hz) and tRNS with cognitive exercises in a regimen protocol of 4 weeks, everyday (Monday to Friday). The study design is a longitudinal study design in which participants receive different tES randomly ordered. Treatments occur for 4 weeks, then 12 weeks of no treatment (wash-out period), repeated for each tES treatment type. Participants have the option of having their choice of music in the background while they perform cognitive exercises.
Inclusion: ability to read, write and speak English fluently; MoCA score between 5 and 24.
Exclusion: Plan to change the medication during any treatment period (5 weeks including the pre-post assessments); Being diagnosed with Parkinson's disease, Parkinsonian dementia, Huntington disease, speech significant aphasia and intellectual disability, major depression/anxiety, bipolar disorder, schizophrenia or any other major mood disorder; Having a history of epileptic seizures or epilepsy; Current substance abuse disorder; Currently participating in another therapeutic study for dementia; Inability to adequately communicate in English; Impaired vision or hearing severe enough to impair performance in cognitive tests.