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Testing 3 Weekly Exercise Amounts for Arthritis Symptoms

Tests 3 weekly exercise amounts in adults with arthritis, including rheumatoid arthritis and gout.

Plain-language title generated from the registry record
Registry title: Dose Response of Exercise for Arthritis Management

Key facts

Where
Columbia, United StatesSee the site

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with a doctor-diagnosed form of arthritis, rheumatoid arthritis, gout, lupus, or fibromyalgia. It tests 3 levels of weekly physical activity.

Age
18 years or older
Sex
All sexes can join.
Disease stage
A doctor-diagnosed form of arthritis, rheumatoid arthritis, gout, lupus, or fibromyalgia. No stage is named.

Main reasons for not taking part

  • Any reason not to exercise, besides arthritis
  • More than 45 min/week of moderate to vigorous activity, measured with an Actigraph
  • Pregnant, breastfeeding, or planning to become pregnant in the next year
  • Uncontrolled high blood pressure
  • Serious cognitive impairment

Read by machine on 12 November 2026.

Where in United States

  • University of South CarolinaColumbia, United StatesContact: Christine PellegriniTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

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Trial details

Who runs it
University of South Carolina
Trial code
NCT06880653
Record updated
3 April 2026
Original description
The purpose of the study is to see examine the effects of 3 different levels of physical activity (45 minutes/week, 90 minutes/week, or 150 minutes/week) on arthritis symptoms.Read full original descriptionShow less

Examination of the Dose Response Relationship Between Physical Activity and Arthritis-Attributable Outcomes

The purpose of the study is to see examine the effects of 3 different levels of physical activity (45 minutes/week, 90 minutes/week, or 150 minutes/week) on arthritis symptoms.

Inclusion: 18 years or older; Have a doctor diagnosed form of arthritis, rheumatoid arthritis, gout, lupus, or fibromyalgia; Ability to read and write in English.

Exclusion: Plan to have a surgery that affects mobility in the next 12 months; Have uncontrolled hypertension (e.g., systolic blood pressure > 160 mmHg or diastolic blood pressure > 100 mmHg); Have a serious cognitive impairment; Not willing to be randomized to any of the 3 conditions, do not believe they could adhere to the goals, or do not believe they could achieve the highest dose of activity (150 minutes/week); Have any contraindications to exercise (besides arthritis); Engage in >45 min/week of Actigraph assessed moderate to vigorous intensity activity; Are pregnant, breastfeeding, or planning to become pregnant in the next year; Are planning to relocate out of the Columbia, SC area in the next 12 months,; Do not have a device compatible with Fitbit.

ClinicalTrials.gov NCT06880653