Comparing High-Tech and Traditional Rehabilitation for Chronic Neuromuscular Diseases
Tests high-tech robotic rehabilitation against traditional rehabilitation in adults with chronic nerve and muscle diseases.
Key facts
- Who runs it
- Istituti Clinici Scientifici Maugeri SpA
- Where
- Genova, Milan, Modena, Montescano, Pavia, Roma, and Telese Terme, ItalySee the 7 sites
- Trial code
- Registry title
- High-Tech Rehabilitation Pathway for Chronic Adult Neuromuscular Diseases - Fit4MedRob-Chronic MND Project
- Status
- Recruiting
- People taking part
- 60 people, planned
- Started
- 28 Apr 2025
- Expected to end
- Dec 2026
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- High-tech rehabilitative treatment
- Rehabilitation
- Record updated
- 4 November 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with a long-lasting neuromuscular disease, such as ALS, CIDP or CMT, who can walk alone or with help. It compares high-tech rehabilitation with traditional rehabilitation.
- Age
- 18 to 80 years
- Sex
- All sexes can join.
- Disease stage
- A confirmed chronic neuromuscular disease (for example ALS, CIDP, CMT).
Main reasons for not taking part
- Unstable medical conditions, such as severe heart disease (NYHA=4) or breathing problems not controlled by ventilation
- Taking part in another clinical trial that could interfere with this one
- Pregnancy
The registry criteria, word for word
Show all 7 criteriaShow less
Who can take part
- Patients with a confirmed diagnosis of chronic neuromuscular diseases (e.g. ALS, CIDP, CMT)
- Patient able to walk independently or with assistance
- Patients capable of understanding and adhering to the study protocol
- Patients who have provided informed consent to participate in the study
Who cannot take part
- Patients with unstable medical conditions (e.g. severe cardiovascular diseases, such as "New York Heart Association" - NYHA=4, respiratory distress not compensated by ventilation) that could interfere, in the clinician's judgment, with their ability to safely participate in the study or to perform the assessments related to the protocol
- Patients currently participating in other clinical trials that could interfere with this study
- Pregnant women
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Where in Italy
- IRCCS Azienda Ospedaliera Universitaria San Martino - GenovaGenova, ItalyContact: Angelo Schenone, MDNot yet recruiting
- Istituti Clinici Scientifici Maugeri IRCCS, Milan InstituteMilan, ItalyContact: Christian Lunetta, MDTaking people
- Azienda Ospedaliero - Universitaria di ModenaModena, ItalyContact: Jessica Mandrioli, MDNot yet recruiting
- Istituti Clinici Scientifici MaugeriMontescano, ItalyContact: Cira Fundarò, MDNot yet recruiting
- Istituti Clinici Scientifici Maugeri IRCCSPavia, ItalyContact: Antonio Nardone, MDNot yet recruiting
- Fondazione Don Carlo Gnocchi ONLUSRoma, ItalyContact: Irene Aprile, MDNot yet recruiting
- Istituti Clinici Scientifici Maugeri IRCCSTelese Terme, ItalyContact: Laura Marcuccio, MDNot yet recruiting
About the trial
What the trial wants to find out
The primary objective is to demonstrate, in a population of chronic neuromuscular disease the non-inferiority of a rehabilitation treatment integrated with robotic and/or technological devices compared to traditional rehabilitation treatment in the level of fatigue.
Read full original descriptionShow less
The main question it aims to answer is:
Are high-tech rehabilitation interventions, including robotic systems, virtual reality, and stabilometric platforms, not inferior to traditional rehabilitation methods in improving balance, motor function, fatigue levels, sarcopenia, cognitive engagement, and overall quality of life in patients with chronic neuromuscular diseases (NMDs)? Researchers will compare a robotic treatment group, that consists in an high-tech rehabilitation, with a control group, that will receive the traditional rehabilitative treatment.
The 2 groups in the trial
- Robotic treatment groupExisting treatment, for comparison
In this arm, patients will undergo in motor and cognitive exercise using the VR device (e.g., VRRS EVO), treatment with proprioceptive exercises on a platform (e.g., GEA MASTER or PROKIN Technobody) to enhance postural control, aerobic exercises on a robotic treadmill (e.g. Walkerview Technobody) and usual physiotherapy treatment, such as passive and active assisted exercises
Treatment: High-tech rehabilitative treatment
- Control groupOther group
The patients will receive the traditional rehabilitative treatment according to the good clinical practice according to the Diagnostic, Therapeutic and Care Pathways of each center involved
Treatment: Rehabilitation
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Clinical Protocol for a Pragmatic Trial on a High-Tech Rehabilitation Pathway for Chronic Adult Neuromuscular Diseases (Fit4MedRob-Chronic MND Project)
- Plain-language title
- Comparing High-Tech and Traditional Rehabilitation for Chronic Neuromuscular DiseasesGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Fit questions
- Built from NCT06881979, who can take part
- Record updated
- 4 November 2026