Camera pill test of the whole bowel for suspected Crohn's disease
Compares a whole-bowel camera pill with colonoscopy in young adults suspected of Crohn's disease.
Plain-language title generated from the registry record
Registry title: Feasibility of a Minimally Invasive Diagnostic Algorithm in Suspected Crohn's Disease
Key facts
- Where
- Esbjerg, Odense C, Svendborg, and Vejle, DenmarkSee the 4 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 40 years old?
Source: NCT06882993, who can take part
Where in Denmark
- Esbjerg Hospital, University Hospital of Southern DenmarkEsbjerg, DenmarkTaking people
- Odense University HospitalOdense C, DenmarkTaking people
- Odense University Hospital - Svendborg HospitalSvendborg, DenmarkTaking people
- Lillebaelt Hospital Vejle, University Hospital of Southern DenmarkVejle, DenmarkTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Esbjerg Hospital - University Hospital of Southern Denmark
- Trial code
- NCT06882993
- Record updated
- 9 September 2026
- Original description
The goal of this clinical trial is to learn whether a camera pill examination of the whole bowel can be used to diagnose Crohn's disease instead of colonoscopy and a small bowel examination (either MRI or camera pill) in patients aged 18-40 years suspected of having Crohn's disease.Read full original descriptionShow less
Feasibility of a Minimally Invasive Diagnostic Algorithm in Suspected Crohn's Disease - a Prospective Comparison of Pan-Enteric Capsule Endoscopy Versus Ileocolonoscopy Plus MR Enterography or Small-Bowel Capsule Endoscopy
The goal of this clinical trial is to learn whether a camera pill examination of the whole bowel can be used to diagnose Crohn's disease instead of colonoscopy and a small bowel examination (either MRI or camera pill) in patients aged 18-40 years suspected of having Crohn's disease.
The main question it aims to answer is:
How many patients examined with a camera pill examination of the whole bowel will have a complete examination of the whole bowel and have a diagnosis made without need for any more examinations?
Researchers will compare with patients examined with colonoscopy and a small bowel examination.
Participants will:
* Be examined with either a camera pill examination of the whole bowel, or a colonoscopy and a small bowel examination * Have their electronic medical records checked to see if a diagnosis has been made * Have an interview every three months if diagnosed with an inflammatory bowel disease or after a year if no disease was found
Inclusion: Clinical suspicion of CD*; Age 18-40 years; Signed informed consent; *A clinical suspicion of CD is based on the following definition:; Diarrhea and/or abdominal pain for more than 1 month (or repeated episodes of diarrhea and/or abdominal pain) and either; fecal calprotectin ≥ 200 mg/kg or; fecal calprotectin ≥ 50 mg/kg plus one or more of the following findings:; C-reactive protein (CRP) > 5 mg/L; Thrombocytosis (> 400 x 109/L); Anemia (hemoglobin < 7.0 mmol/L for women and < 8.0 mmol/L for men or a decrease > 0.5 mmol/L compared to the usual level); Prolonged fever (> 37.5 ◦C for more than 2 weeks); Weight loss (≥ 3 kg or ≥ 5% compared to the normal body weight); Perianal abscess / fistula; Family history of inflammatory bowel disease.
Exclusion: Previous intestinal resection; Intake of NSAIDs or acetylsalicylic acid ≤ 4 weeks before inclusion, except low-dose, prophylactic acetylsalicylic acid (≤ 150 mg per day); Intake of opioid or opioid-like medications ≤ 1 week before inclusion; Inability to comply with protocol requirements, e.g. for reasons including alcohol or recreational drug abuse; Positive serologic markers for celiac disease; Known gastrointestinal disorder other than functional gastrointestinal disorders; Renal failure defined by a plasma-creatinine above the normal reference range; Positive stool polymerase chain reaction for pathogenic bacteria; Positive stool polymerase chain reaction for intestinal parasites; Suspected or established acute bowel obstruction (ileus); Pregnancy or lactation.