Immediate lymphatic reconstruction during lymph node removal surgery for melanoma
Studies lymphovenous bypass done during surgery in melanoma patients, for swelling risk.
Key facts
- Who runs it
- M.D. Anderson Cancer Center
- Where
- Houston, United StatesSee the site
- Trial code
- Registry title
- Immediate Lymphatic Reconstruction After Lymphadenectomy in Melanoma Patients: a Parallel Cohort Pilot Study
- Status
- Recruiting
- People taking part
- 20 people, planned
- Started
- 10 Jun 2026
- Expected to end
- 1 Sept 2028
- Type of study
- Interventional, 2 groups
- Treatments tested
- Lymphovenous bypass (LVB)
- Record updated
- 18 June 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with melanoma who are having surgery to remove lymph nodes in the armpit or groin. It tests a lymph vessel bypass done during that surgery to help prevent lymphedema.
- Age
- 18 years or older
- Sex
- All sexes can join
- Disease stage
- Melanoma, with planned surgery to remove lymph nodes (ALND or ILND)
- Earlier treatment
- Cannot join if taking anticoagulants (blood thinners) within 7 days before surgery
Main reasons for not taking part
- Taking anticoagulants within 7 days before surgery
- Known to be pregnant at the time of surgery
- BMI greater than 50.0
The registry criteria, word for word
Show all 7 criteriaShow less
Who can take part
- Participants greater than or equal to 18 years of age
- Participants willing to participate
- Participants able to complete informed consent
- Participants with a diagnosis of Melanoma undergoing ALND or ILND
Who cannot take part
- Participant staking anticoagulants within 7 days prior to surgery
- Participants that are known to be pregnant at the time of surgery
- Participants with BMI greater than 50.0
Where in United States
- MD Anderson Cancer CenterHouston, United StatesContact: Ashleigh M Francis, MDTaking people
About the trial
What the trial wants to find out
To learn if LBP can help to prevent lymphedema when it is performed at the time of surgery rather than after a patient has already developed the disease.
The 2 groups in the trial
- Upper extremity group recieving ALNDTreatment being tested
Participants will be recruited pre-operatively by their treating physicians.
Treatment: Lymphovenous bypass (LVB)
- Lower extremity group getting ILNDTreatment being tested
Participants will be recruited pre-operatively by their treating physicians.
Treatment: Lymphovenous bypass (LVB)
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Immediate Lymphatic Reconstruction After Lymphadenectomy in Melanoma Patients: a Parallel Cohort Pilot Study
- Plain-language title
- Immediate lymphatic reconstruction during lymph node removal surgery for melanomaGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Record updated
- 18 June 2026