Texture and Color Enhancement Imaging for Bowel Inflammation in Inflammatory Bowel Disease
Compares a new endoscope light mode with standard light in adults with bowel inflammation.
Plain-language title generated from the registry record
Registry title: Texture and Color Enhancement Imaging (TXI) for Inflammation Assessment in Patients With Inflammatory Bowel Diseases
Key facts
- Where
- Ulm, GermanySee the site
Where in Germany
- Ulm University HospitalUlm, GermanyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Ulm
- Trial code
- NCT06892990
- Record updated
- 2 May 2025
- Original description
In the context of the COLORIZE study, it is being tested whether the endoscopic light mode Texture and Color Enhancement Imaging (TXI) is non-inferior to the standard White Light Endoscopy (WLE) in assessing inflammatory activity in patients with Inflammatory Bowel Disease (IBD). For this purpose, ileocolonoscopy is performed on patients diagnosed with IBD, and standardized image documentation will be carried out in both WLE and TXI modes. Step biopsies are taken, and clinically validated, endoscopic, and histological scores are used.Read full original descriptionShow less
Texture and Color Enhancement Imaging (TXI) for Real-time Prediction of Histologic Changes in Patients With Inflammatory Bowel Diseases: a Comparison of White Light Endoscopy (WLE) Versus TXI
In the context of the COLORIZE study, it is being tested whether the endoscopic light mode Texture and Color Enhancement Imaging (TXI) is non-inferior to the standard White Light Endoscopy (WLE) in assessing inflammatory activity in patients with Inflammatory Bowel Disease (IBD). For this purpose, ileocolonoscopy is performed on patients diagnosed with IBD, and standardized image documentation will be carried out in both WLE and TXI modes. Step biopsies are taken, and clinically validated, endoscopic, and histological scores are used.
Inclusion: Histologically confirmed inflammatory bowel disease (ulcerative colitis or Crohn\'s disease); Age ≥ 18 years.
Exclusion: Severe coagulation disorder; Post (procto-) colectomy; Endoscopically impassable stenosis in the left hemi-colon; ASA status \> 2 points; BBPS \< 6 points (or \< 2 points per segment); Pregnancy, lactation.