Under construction – not a live service
Sign in
Taking people in United StatesPhase 3

Tests magnesium with prochlorperazine for migraine pain in emergency patients

Tests magnesium added to prochlorperazine for migraine pain in adults.

Plain-language title generated from the registry record
Registry title: Effectiveness of Magnesium in Addition to Prochlorperazine for the Treatment of Migraines

Key facts

Where
Oak Lawn, United StatesSee the site
Phase
Phase 3

Where in United States

  • Advocate Christ Medical Center Emergency DepartmentOak Lawn, United StatesTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Wake Forest University Health Sciences
Trial code
NCT06904287
Record updated
22 January 2026
Original description
The purpose of this research study is to find out if using magnesium in addition to prochlorperazine will help reduce your migraine pain.Read full original descriptionShow less

Evaluating the Effectiveness of Magnesium in Addition to Prochlorperazine for the Treatment of Migraines in the Emergency Department

The purpose of this research study is to find out if using magnesium in addition to prochlorperazine will help reduce your migraine pain.

Inclusion: Age ≥ 18 years or older; Able to provide informed consent; English speaking; Primary diagnosis of migraine. Patient with a previous diagnosis of migraine, who experience headaches with typical migraine features (e.g at least 2-3 of the following: recurrent, unilateral, pounding or throbbing in nature, associated with nausea), AND with a clinical exclusion of migraine mimics.

Exclusion: Consumption of study drug within 48 hours prior to enrollment; Previously enrolled in this trial during a different patient encounter; Allergy or sensitivity to study drug; Stated history of renal insufficiency; Documented history of myasthenia gravis; Pregnancy defined as a positive urine HCG.

ClinicalTrials.gov NCT06904287