AI Heart Tracing Tool to Find Pulmonary Hypertension in Interstitial Lung Disease
Tests an AI heart tracing tool in adults with interstitial lung disease.
Plain-language title generated from the registry record
Registry title: Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension
Key facts
- Where
- Albuquerque, Ann Arbor, Birmingham, Bossier City, Boston, Buffalo, Charleston, Chicago, Cleveland, Dallas, Denver, Hannibal, Houston, Indianapolis, Jackson, Knoxville, Lexington, Little Rock, Minneapolis, Morgantown, New York, Oklahoma City, Omaha, Orlando, Philadelphia, Phoenix, Reno, Richmond, Riverside, Royal Oak, Salt Lake City, San Antonio, Shreveport, Springfield, and Winston-Salem, United StatesSee the 41 sites
Where in United States
- University of New MexicoAlbuquerque, United StatesTaking people
- University of Michigan - Michigan MedicineAnn Arbor, United StatesTaking people
- University of Alabama at BirminghamBirmingham, United StatesTaking people
- Willis Knighton HealthBossier City, United StatesTaking people
- Brigham and Women's HospitalBoston, United StatesTaking people
- University of BuffaloBuffalo, United StatesTaking people
- Medical University of South CarolinaCharleston, United StatesTaking people
- Northwestern UniversityChicago, United StatesTaking people
- University of Illinois HealthChicago, United StatesTaking people
- University Hospitals Cleveland Medical Center*Cleveland, United StatesTaking people
- Baylor University Medical CenterDallas, United StatesTaking people
- National Jewish HealthDenver, United StatesTaking people
- Hannibal Regional Healthcare SystemHannibal, United StatesTaking people
- Baylor College of MedicineHouston, United StatesTaking people
- Houston Methodist HospitalHouston, United StatesTaking people
- The University of Texas Health Science Center HoustonHouston, United StatesTaking people
- Community Health NetworkIndianapolis, United StatesTaking people
- Indiana University Health Methodist HospitalIndianapolis, United StatesTaking people
- University of Mississippi Medical CenterJackson, United StatesTaking people
- University of TennesseeKnoxville, United StatesTaking people
- University of KentuckyLexington, United StatesTaking people
- University of ArkansasLittle Rock, United StatesTaking people
- University of MinnesotaMinneapolis, United StatesTaking people
- West Virginia University HospitalMorgantown, United StatesTaking people
- Weill Cornell University Medical CollegeNew York, United StatesTaking people
- University of OklahomaOklahoma City, United StatesTaking people
- CHI Health Creighton University Medical Center-Bergan MercyOmaha, United StatesTaking people
- AdventHealth OrlandoOrlando, United StatesTaking people
- Temple University Of the Commonwealth System of Higher EducationPhiladelphia, United StatesTaking people
- Thomas Jefferson UniversityPhiladelphia, United StatesTaking people
- Banner University Medical CenterPhoenix, United StatesTaking people
- Dignity Health - St. Joseph's Hospital and Medical Center-Norton Thoracic InstitutePhoenix, United StatesTaking people
- Renown Regional Medical CenterReno, United StatesTaking people
- Virginia Commonwealth UniversityRichmond, United StatesTaking people
- HCA Riverside Community HospitalRiverside, United StatesTaking people
- Corewell HealthRoyal Oak, United StatesTaking people
- University of UtahSalt Lake City, United StatesTaking people
- HCA Research Institute - Methodist HospitalSan Antonio, United StatesTaking people
- Louisiana State University Health ShreveportShreveport, United StatesTaking people
- Mercy Hospital SpringfieldSpringfield, United StatesTaking people
- Southeastern Research CenterWinston-Salem, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Tempus AI
- Trial code
- NCT06911632
- Record updated
- 3 November 2026
- Original description
MOMENTOUS is a multi-center, randomized study to prospectively evaluate the performance of an ECG-based AI device to predict whether participants with interstitial lung disease (ILD) are at high risk of undiagnosed pulmonary hypertension.Read full original descriptionShow less
MOMENTOUS Study (iMpact Of an Ecg ai ModEl oN The Diagnosis Of pUlmonary hypertenSion)
MOMENTOUS is a multi-center, randomized study to prospectively evaluate the performance of an ECG-based AI device to predict whether participants with interstitial lung disease (ILD) are at high risk of undiagnosed pulmonary hypertension.
Inclusion: 18 years or older at the time of consent; A known diagnosis of interstitial lung disease; Diffusing capacity for carbon monoxide (DLCO) <30% predicted, collected within 6 months prior to consent; Willing and able to provide informed consent and undergo all study-specific procedures, including echo and RHC, if required.
Exclusion: A RHC was completed within the previous 1 year or ordered and not yet completed at the time of consent; There is a severe concomitant illness limiting life expectancy to less than 6 months (at the discretion of the investigator); A known diagnosis of pulmonary hypertension (including patients prescribed a therapy specifically for pulmonary arterial hypertension (PAH)); A contraindication to RHC exists (for example, pregnancy or mechanical right heart valve); LV ejection fraction ≤ 40% on most recent echo or cardiac MRI, if available; Unclassifiable Tempus PH ECG risk result after up to 2 ECG acquisitions; Physician decision that if a patient is directed to RHC by the study protocol, the potential risks of RHC outweigh the potential benefits; There is a medical or social factor that makes the patient a poor candidate for the study and/or unlikely to be able to comply with the study protocol or complete study procedures (at the discretion of the investigator).