Measuring Visual Brain Responses in People With Psychotic Disorders
Uses EEG brain recordings to look for markers of psychosis in adults.
Plain-language title generated from the registry record
Registry title: Visual Perception in Schizophrenia
Key facts
- Where
- Rochester, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT06911931, who can take part
Where in United States
- University of RochesterRochester, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Rochester
- Trial code
- NCT06911931
- Record updated
- 12 November 2025
- Original description
This study aims to identify novel markers of psychosis using electroencephalography (EEG).Read full original descriptionShow less
Visual Perception in Schizophrenia: Assessing Predictive Processing in the Earliest Stages of the Visual Cortical Hierarchy
This study aims to identify novel markers of psychosis using electroencephalography (EEG).
Inclusion: All Subjects; Aged 18-65; 20/32 visual acuity or better (using in-house optical correction, if necessary); An ability to speak English well enough to complete study assessments and to consent to the study; Subjects with Schizophrenia-Spectrum Disorder; Meets DSM-5 diagnostic criteria for schizophrenia, schizoaffective disorder, or schizophreniform disorder as confirmed by the Structured Interview for DSM-5 (SCID-5); Subjects with Bipolar Disorder; Meets DSM-5 diagnostic criteria for bipolar disorder (type I, II, or unspecified) as confirmed by the Structured Interview for DSM-5 (SCID-5).
Exclusion: Presence of characteristics that could impair one's ability to comprehend the nature of the study, provide informed consent, or understand the assessment questions, including the following:; Subject cannot read and understand the instructions well enough to complete the tasks or cannot provide informed consent; Intellectual impairment (WRAT-5 score < 70) (at the discretion of experimenter); Actively intoxicated, as shown via patient self-report or staff report; Substance use disorder in the past 3 months; Subject considered high risk for suicidal acts (i.e., active suicidal ideation as determined by clinical interview OR any suicide attempt in 30 days prior to screening); Subject violence (involving severe/lethal means or violence occurring in prior 6 months) or extreme agitation; Being in a current manic state; Head injury with loss of consciousness greater than 10 minutes (at the discretion of the experimenter); Subject has had electroconvulsive therapy (ECT) in the past 8 weeks; Diagnosed with a neurological condition (tumor, stroke, brain injury) or neurological disorder, including seizure disorders. Diagnosed with pervasive developmental disorder (phone screen or medical records); Lazy eye or squint or other known ocular pathology; Daily antidepressant, mood stabilizer or antipsychotic medication use in the last 6 months, or benzodiazepine use during the prior 2 days (self-disclosure); iii. First-degree relative(s) with a schizophrenia spectrum disorder (based on subject self-report) or bipolar disorder; Daily antidepressant, mood stabilizer or antipsychotic medication use in the last 6 months, or benzodiazepine use during the prior 2 days; Any lifetime psychotic disorder or history of psychiatric hospitalization (self disclosure); Any lifetime psychotic disorder (as assessed by SCID/or SSD); History of psychiatric hospitalization; First-degree relative(s) with a schizophrenia spectrum disorder (based on subject self-report) or bipolar disorder; All subjects; Healthy Control Subjects; Case-match Control Non-ill Subjects; Recurrent depressive episodes or being in a current depressive episode (as assessed by SCID/or SSD); Persistent threshold psychotic symptoms; Bipolar Subjects; Persistent threshold psychotic symptoms.