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Studying genetic risk scores in people with colon cancer in Brazil

Studies genetic information from people with colon cancer to build a risk score.

Plain-language title generated from the registry record
Registry title: Development of Polygenic Risk Scores in Colon Cancer Patients Through the Study of Ancestry and Diversity in Genetic Maps of the Brazilian Population - ORIGEM Project

Key facts

Where
Brasília, Curitiba, Fortaleza, Recife, Rio de Janeiro, Salvador, and São Paulo, BrazilSee the 9 sites

Where in Brazil

  • Instituto D'Or de Pesquisa e EnsinoBrasília, BrazilNo longer taking part
  • Instituto D'Or de Pesquisa e EnsinoCuritiba, BrazilNo longer taking part
  • Instituto D'Or de Pesquisa e EnsinoFortaleza, BrazilNo longer taking part
  • Instituto D'Or de Pesquisa e EnsinoRecife, BrazilNo longer taking part
  • Instituto D'Or de Pesquisa e EnsinoRio de Janeiro, BrazilNo longer taking part
  • CPOC - Centro de Pesquisa Oncológica e Clínica, faz parte do Complexo Associação Obras Sociais lrmã Dulce (AOSID)Salvador, BrazilNo longer taking part
  • Instituto D'Or de Pesquisa e EnsinoSalvador, BrazilNo longer taking part
  • Instituto D'or de Pesquisa e EnsinoSão Paulo, BrazilNo longer taking part
  • Instituto do Câncer do Estado de São PauloSão Paulo, BrazilNo longer taking part

Questions to ask the study team

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  2. Are travel costs paid?
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  4. What happens if I want to stop?
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Trial details

Who runs it
D'Or Institute for Research and Education
Trial code
NCT06917794
Record updated
8 April 2025
Original description
Development of a polygenic risk score based on somatic and germline genetic information from patients with colorectal cancerRead full original descriptionShow less

Development of Polygenic Risk Scores in Colon Cancer Patients Through the Study of Ancestry and Diversity in Genetic Maps of the Brazilian Population - ORIGEM Project

Development of a polygenic risk score based on somatic and germline genetic information from patients with colorectal cancer

Inclusion: > 18 years; Histologically confirmed diagnosis of colorectal cancer; Have available tumor material for somatic sequencing, obtained from biopsy or routine surgery; Sign the informed consent form (ICF) for the study.

Exclusion: Pregnants.

ClinicalTrials.gov NCT06917794