Exercise with or without a low-calorie diet for children with Down syndrome
Tests brisk walking with or without a low-calorie diet in overweight children with Down syndrome.
Plain-language title generated from the registry record
Registry title: Aerobic Exercise With and Without Low Calorie Diet on Adiposity and BMI of Down Syndrome
Key facts
- Where
- Lahore, PakistanSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for overweight or obese children with Down syndrome, aged 8 to 16 years, in generally stable health.
- Age
- 8 to 16 years
- Sex
- Girls and boys can both join.
- Disease stage
- Overweight or obese: BMI-for-age at or above the 85th percentile (overweight) or at or above the 95th percentile (obese).
- Earlier treatment
- Children cannot have taken part in a weight loss exercise program before. They cannot have followed a specific diet plan in the last 6 months.
Main reasons for not taking part
- History of any previous medical disease
- Medication that could affect weight or metabolism
- Physical disabilities that prevent safe aerobic exercise
- Dietary restrictions or food allergies
- Severe cognitive impairments that prevent taking part in the exercise program
This trial only enrols participants with Down syndrome. The registry sentence this rests on: Effects of Aerobic Exercise With and Without Low Calorie Diet on Adiposity and BMI of Overweight and Obese Children With Down Syndrome
Read by machine on 12 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 8 and 16 years old?
Source: NCT06943170, who can take part
Where in Pakistan
- Jannat ArshadLahore, PakistanContact: Jannat Arshad, MS-PTTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Riphah International University
- Trial code
- NCT06943170
- Record updated
- 24 April 2025
- Original description
Down syndrome (DS) is caused by trisomy 21, or the presence of an extra copy of chromosome 21. A calibrated weight scale is used to measure participants' weight accurately. A stadiometer measures participants' height to the nearest millimeter. A flexible non-stretchable waist circumference tape is used to assess abdominal obesity. Body mass index (BMI, ratio of height and weight, expressed as kg/m2 6-Min Walk is a test to evaluate aerobic fitness level. Brisk Walk, a type of moderate intensity aerobic exercise can be an effective component of a weight loss program for overweight and obese children with Down syndrome. The aim of this study to compare the effects of aerobic exercise alone versus aerobic exercise combined with a low calorie diet, to provide insights into optimal inte A randomized controlled trial will be conducted. The study will be conducted at Rehab Clinic, Lahore in a total duration of 10 months. Sample size will be 22. There will be two study groups, Group I: Aerobic Exercise with Low calorie diet and Group II: Aerobic Exercise without Low calorie diet. Non-Probability Convenient sampling technique will be used to collect the data.Read full original descriptionShow less
Effects of Aerobic Exercise With and Without Low Calorie Diet on Adiposity and BMI of Overweight and Obese Children With Down Syndrome
Down syndrome (DS) is caused by trisomy 21, or the presence of an extra copy of chromosome 21. A calibrated weight scale is used to measure participants' weight accurately. A stadiometer measures participants' height to the nearest millimeter. A flexible non-stretchable waist circumference tape is used to assess abdominal obesity. Body mass index (BMI, ratio of height and weight, expressed as kg/m2 6-Min Walk is a test to evaluate aerobic fitness level. Brisk Walk, a type of moderate intensity aerobic exercise can be an effective component of a weight loss program for overweight and obese children with Down syndrome. The aim of this study to compare the effects of aerobic exercise alone versus aerobic exercise combined with a low calorie diet, to provide insights into optimal inte A randomized controlled trial will be conducted. The study will be conducted at Rehab Clinic, Lahore in a total duration of 10 months. Sample size will be 22. There will be two study groups, Group I: Aerobic Exercise with Low calorie diet and Group II: Aerobic Exercise without Low calorie diet. Non-Probability Convenient sampling technique will be used to collect the data.
Inclusion: Age (8-16) years; Both Genders (Male and Female); BMI-for-age percentile (at or above 85th percentile is overweight, and at or above 95th percentile is considered as obese); Children with generally stable health condition, without significant co-morbidities that might affect diet or exercise interventions; Consent form signed by parents, along with written approval by the physician.
Exclusion: History of any previous medical disease; Previous Participation in any Weight Loss Exercise Program; Exclusion of children on medication that could affect weight or metabolism; Children with dietary restrictions or food allergies; Participants following any specific diet plan from last 6 months; Children with physical disabilities that prevent them from safely participating in aerobic exercise; Children with severe cognitive impairments that prevent them from engaging in exercise program.