Psychological Trauma, Post-Traumatic Stress Disorder, and Resilience in Adults With Congenital Heart Disease
Key facts
- Who runs it
- Dartmouth-Hitchcock Medical Center
- Where
- Columbus, Lebanon, and Washington D.C., United StatesSee the 3 sites
- Trial code
- Status
- Recruiting
- People taking part
- 1,000 people, planned
- Started
- 1 Sept 2025
- Planned end
- Aug 2026
- Type of study
- Observational
- Treatments tested
- Other
- Record updated
- 25 March 2026
Who can take part
- Age
- 18 years and older
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
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Who can take part
- Congenital heart disease diagnosis, age >= 18 years
- Enrolled in CHI registry
- English proficiency for survey completion
- Access to an internet connection. Can be via computer or handheld device
Who cannot take part
- No diagnosis of congenital heart disease
- Age < 18 years
- Any who opt out
- Not enrolled in CHI registry/unable to access Internet
Where in United States
- Nationwide Children's HospitalColumbus, United StatesContact: Jamie Jackson, Ph.D.Not yet recruiting
- Dartmouth Hitchcock Medical CenterLebanon, United StatesContact: David J Harrison, M.D.Taking people
- Children's National Medical CenterWashington D.C., United StatesContact: Anitha S John, M.D., Ph.D.Not yet recruiting
About the trial
What the trial wants to find out
The purpose of this study, entitled "Psychological trauma, post-traumatic stress disorder, and resilience in adults with congenital heart disease in a large population sample", is to evaluate for exposures during a lifetime with congenital heart disease that may be associated with higher likelihood of developing PTSD.
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Primary aim:
- Identify individual patient characteristics (medical, psychosocial, socioeconomic, etc.) that are associated with a diagnosis of PTSD.
Secondary aims:
* Calculate the prevalence of those meeting PTSD criteria in the ACHD population using the "gold standard" diagnostic clinician interview, while using the same data to validate a PTSD screening self-report survey in the ACHD population. * Determine the role of resilience in ACHD patients using a validated screening survey to assess its protective role toward PTSD.
Hypotheses:
* There are certain exposures (e.g. post-surgical pain, ICU delirium, bullying due to CHD) that are associated with a higher incidence and odds of meeting PTSD criteria. * "Gold standard" diagnostic interviews will most accurately estimate the prevalence of PTSD in ACHD which has been overestimated on prior screening-based studies, although the scope of the problem is still great. * Patients with a higher resilience score will show an association with a lower risk of PTSD.
The group in the trial
- Overall cohort
Adults age \>= 18-years with a diagnosis of congenital heart disease. Congenital heart disease will be defined by previously published classification including those listed in the American Heart Association/ American College of Cardiology guidelines for the care of adults with congenital heart disease.
Treatment: Other
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Record updated
- 25 March 2026