Congenital heart disease trials in United States

In United States 64 Also abroad 194

64 trials · From ClinicalTrials.gov, checked 13 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
iPSC Repository of Pediatric Cardiovascular Disease
Where
Columbus
People
3,000
Run by
Mingtao Zhao
See details and how to joinNCT05550324
No phaseNot yet taking people in United States
UltraTrac for Cardiac Output Monitoring in Congenital Heart Disease
Where
Minneapolis
Age
0 years to 80 years
People
70
Run by
University of Minnesota
See details and how to joinNCT07866573
Phase 1/2Taking people
Butyric Acid Supplementation for Gut Improvement After Cardiac Surgery in Kids
Where
Omaha
Age
1 month to 3 years
People
105
Run by
University of Nebraska
See details and how to joinNCT06882772
No phaseEnrolling by invitation
EXCOR Active Driving System for the EXCOR Pediatric VAD IDE Study
Where
Ann Arbor, Aurora, Austin, Boston, Charlotte, Chicago, Cincinnati, Gainesville, Houston, Los Angeles, Milwaukee, New York, Palo Alto, Philadelphia, Salt Lake City, St Louis, Washington D.C.
Age
Up to 21 years
People
40
Run by
Berlin Heart, Inc
See details and how to joinNCT05610787
No phaseTaking people
Starlight Cardiovascular Lifeline Ductus Arteriosus Stent IDE Study
Where
Aurora, Baltimore, Boston, Cincinnati, Columbus, Houston, Los Angeles, Philadelphia, San Diego, Seattle, Stanford
Age
1 Minute to 6 months
People
45
Run by
Starlight Cardiovascular Inc
See details and how to joinNCT07114718
No phaseTaking people
Implementing Models for Mechanical Circulatory Support Presurgical Assessment in Congenital Heart Disease Treatment
Where
Atlanta, Chicago, Gainesville, New York, Palo Alto
People
36
Run by
Columbia University
See details and how to joinNCT03891160
No phaseTaking people
A Pragmatic Clinical Trial of the WE BEAT Well-Being Education Program in Adolescent Congenital Heart Disease: WE BEAT CHD Study
Where
Ann Arbor, Atlanta, Aurora, Boston, Charleston, Cincinnati, Lexington, New York, Philadelphia, Pittsburgh, Salt Lake City, Stanford, St Louis
Age
12 years to 17 years
People
390
Run by
Carelon Research
See details and how to joinNCT07525843
No phaseTaking people
Fontan Associated Liver Disease and the Evaluation of Biomarkers for Disease Severity Assessment
Where
Bethesda
Age
18 years to 100 years
People
100
Run by
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
See details and how to joinNCT05213598
Phase 3Taking people
Effect of Sacubitril-Valsartan on Cardiac Structure and Function
Where
Rochester
Age
18 years and over
People
45
Run by
Mayo Clinic
See details and how to joinNCT06693674
No phaseTaking people
Technical and Translational Development of Cardiovascular Magnetic Resonance (CMR) Imaging
Where
Bethesda
Age
7 years to 100 years
People
5,000
Run by
National Heart, Lung, and Blood Institute (NHLBI)
See details and how to joinNCT03581318
No phaseTaking people
Skin Pigment/Pulse Oximeter in Congenital Heart Disease (CHD)
Where
New York
Age
Up to 18 years
People
24
Run by
Icahn School of Medicine at Mount Sinai
See details and how to joinNCT06575270
No phaseTaking people
BOND: Direct Breastfeeding to Enhance Maternal and Infant Health in Congenital Heart Disease
Where
Ann Arbor, Atlanta, Aurora, Boston, Charleston, Chicago, Cincinnati, Kansas City, Lexington, Los Angeles, Memphis, New York, Phoenix, Pittsburgh, Salt Lake City, St Louis
Age
18 years and over
People
266
Run by
Carelon Research
See details and how to joinNCT07582848
No phaseTaking people
Prenatally-initiated Psychological Intervention for Mothers of Infants With Congenital Heart Disease (CHD)
Where
Ann Arbor, Atlanta, Aurora, Boston, Charleston, Chicago, Cincinnati, Kansas City, Lexington, Los Angeles, Memphis, New York, Phoenix, Pittsburgh, Salt Lake City, St Louis
Age
18 years and over
People
210
Run by
Carelon Research
See details and how to joinNCT07582861
No phaseEnrolling by invitation
Heart2Heart for Teens With CHD
Where
Columbus
Age
12 years to 18 years
People
90
Run by
Kristen Fox
See details and how to joinNCT07764510
Phase 4Taking people
Continuous vs Intermittent Ketorolac for Pain Control in Peds CV Surgery
Where
Phoenix
Age
3 months to 59 months
People
166
Run by
Phoenix Children's Hospital
See details and how to joinNCT04040452
No phaseTaking people
Cord Clamping Among Neonates With Congenital Heart Disease
Where
Baltimore, Birmingham, Columbia, Columbus, Durham, Gainesville, Houston, Jackson, Kansas City, Los Angeles, Nashville, Orange, Palo Alto, Philadelphia, Salt Lake City, San Antonio, San Diego, St Louis
Age
37 weeks to 42 weeks
People
500 worldwide
Run by
Carl Backes, MD
See details and how to joinNCT06153459
Phase 2Taking people
Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System
Where
Dallas, Durham, New York, Palo Alto, Seattle
Age
0 years to 16 years
People
50
Run by
Stanford University
See details and how to joinNCT06080074
Phase 3Taking people
NO During CPB in Neonates to Reduce Risk of AKI
Where
Cincinnati
Age
1 day to 31 days
People
40
Run by
Children's Hospital Medical Center, Cincinnati
See details and how to joinNCT04216927
No phaseTaking people
Longitudinal Validation of CIRC Technologies
Where
Cleveland
Age
18 years and over
People
1,000
Run by
The Cleveland Clinic
See details and how to joinNCT07081711
No phaseTaking people
Examining Genetic Factors That Affect the Severity of 22q11.2 Deletion Syndrome
Where
New York
People
1,000
Run by
Albert Einstein College of Medicine
See details and how to joinNCT00556530
No phaseNot yet taking people in United States
Observational Data Collection for Blood Hemoglobin Algorithm Validation in Pediatrics
Where
Boston
Age
0 days to 21 years
People
100
Run by
Boston Children's Hospital
See details and how to joinNCT07706140
No phaseTaking people
COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction
Where
Atlanta, Aurora, Birmingham, Boston, Charlottesville, Cincinnati, Columbus, Dallas, Durham, Lexington, Little Rock, Los Angeles, Memphis, Murray, Nashville, New York, Philadelphia, Pittsburgh, Rochester, San Antonio, San Francisco, Seattle, St Louis
People
108
Run by
Edwards Lifesciences
See details and how to joinNCT02744677
No phaseTaking people
HFNC vs NIPPV Following Extubation
Where
Atlanta
Age
Up to 1 year
People
200
Run by
Emory University
See details and how to joinNCT05869825
No phaseTaking people
PRecision Integrated Saturation Monitor
Where
Memphis
Age
0 months to 12 months
People
100
Run by
Le Bonheur Children's Hospital
See details and how to joinNCT07686341
No phaseTaking people
Molecular Genetics of Heterotaxy and Related Congenital Heart Defects
Where
Indianapolis
People
2,000
Run by
Indiana University
See details and how to joinNCT02432079