Tests peer mentoring to reduce alcohol use in pregnant women in South Africa
Tests peer mentoring to cut alcohol use in pregnant and breastfeeding women.
Plain-language title generated from the registry record
Registry title: Mentor Moms+ Study
Key facts
- Where
- Cape Town and Saldanha Bay, South AfricaSee the 2 sites
Where in South Africa
- Saldanha Bay Municipality ClinicCape Town, South AfricaNot yet recruiting
- Saldanha Bay ClinicsSaldanha Bay, South AfricaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of California, Los Angeles
- Trial code
- NCT06962592
- Record updated
- 2 July 2026
- Original description
The goal of this study is to adapt an existing evidence based intervention for use in pregnant and lactating people (PLP) who use alcohol. Through the pilot RCT, we aim to understand if tailored intervention, Mentor Mothers+, is effective in reducing alcohol use (primary outcome) and improving antiretroviral (PrEP or ART) adherence (secondary outcomes) among pregnant and breastfeeding women living with and without HIV in a community heavily burdened by this syndemic.Read full original descriptionShow less
A Community-based Adaptation of a Peer-led Intervention to Address Alcohol Use and HIV Risk in Pregnant Women in South Africa (Mentor Moms+)
The goal of this study is to adapt an existing evidence based intervention for use in pregnant and lactating people (PLP) who use alcohol. Through the pilot RCT, we aim to understand if tailored intervention, Mentor Mothers+, is effective in reducing alcohol use (primary outcome) and improving antiretroviral (PrEP or ART) adherence (secondary outcomes) among pregnant and breastfeeding women living with and without HIV in a community heavily burdened by this syndemic.
The investigators will conduct an pilot randomized control trial in 100 pregnant women, recruited during antenatal care (ANC) visits within the Saldanha Bay Municipality clinic in Cape Town, South Africa. The RCT will involve the delivery of brief, individual motivational interviewing sessions provided by trained mentor mothers from the community who are on either PrEP (living without HIV) or ART (living with HIV) and who stopped or reduced alcohol use during pregnancy. The enrolled participants will be followed for a 6-month period spanning both pregnancy and postpartum stages.
Inclusion: • ≥ 16 years; Pregnancy confirmed; reported alcohol use during pregnancy (in last 2 months); lives within 20 kilometers of the study facility; able and willing to consent to study participation.
Exclusion: Individuals not meeting the above criteria will be excluded.