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Using Speech to Predict Psychosis Relapse

Studies whether speech patterns can predict relapse in people with psychosis.

Plain-language title generated from the registry record
Registry title: Predicting Psychotic Relapse Using Speech-Based Early Detection

Key facts

Where
London, Montreal, and Québec, CanadaSee the 3 sites

Where in Canada

  • Robarts Research InstituteLondon, CanadaTaking people
  • Douglas Mental Health University InstituteMontreal, CanadaTaking people
  • VitamQuébec, CanadaTaking people

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Trial details

Who runs it
Douglas Mental Health University Institute
Trial code
NCT06978894
Record updated
18 May 2025
Original description
Psychotic disorders, including schizophrenia and affective psychosis, are severe mental health conditions marked by recurrent episodes that contribute to long-term disability. Relapses, characterized by the re-emergence of psychotic symptoms after remission, are a critical factor in the progression of these disorders, increasing risks such as suicide, cognitive impairment, and unemployment. This study aims to develop a novel, speech-based digital model to predict relapses in individuals with psychosis. Building on previous research into language abnormalities in schizophrenia, the study will employ a longitudinal design across Early Psychosis Intervention (EPI) clinics in Ontario and Quebec to advance relapse predictionRead full original descriptionShow less

Predicting Psychotic Relapse Using Speech-Based Early Detection

Psychotic disorders, including schizophrenia and affective psychosis, are severe mental health conditions marked by recurrent episodes that contribute to long-term disability. Relapses, characterized by the re-emergence of psychotic symptoms after remission, are a critical factor in the progression of these disorders, increasing risks such as suicide, cognitive impairment, and unemployment. This study aims to develop a novel, speech-based digital model to predict relapses in individuals with psychosis. Building on previous research into language abnormalities in schizophrenia, the study will employ a longitudinal design across Early Psychosis Intervention (EPI) clinics in Ontario and Quebec to advance relapse prediction

Inclusion: Age must be 16 years and older; Diagnosis must meet DSM-5 criteria for psychotic disorders, including schizophrenia, schizoaffective disorder, or related conditions; Fluency in English or French; Must be currently receiving treatment through an EPI program.

Exclusion: Severe comorbid speech or language disorders (e.g., aphasia); Primary diagnosis of non-psychotic disorders; Inability to provide consent or complete assessments.

ClinicalTrials.gov NCT06978894