Schizophrenia trials in Canada

In Canada 40 Also abroad 470

40 trials · From ClinicalTrials.gov, checked 10 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
A Study to Evaluate the Long-term Safety and Tolerability of Xanomeline and Trospium Chloride for the Treatment of Psychiatric Disorders in Children and Adolescents
Where
Calgary, Edmonton, Kingston, Montreal, Toronto
Age
5 years to 17 years
People
400 worldwide
Run by
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
See details and how to joinNCT07424404 · EU 2025-524062-16-00
No phaseTaking people
Magnetic Seizure Therapy for Schizophrenia - Trial
Where
Toronto, Vancouver
Age
18 years and over
People
80
Run by
Centre for Addiction and Mental Health
See details and how to joinNCT06672588
No phaseTaking people
Theta-Burst Transcranial Magnetic Stimulation for Treatment-Resistant Auditory Hallucinations
Where
Montreal
Age
18 years and over
People
12
Run by
Ciusss de L'Est de l'Île de Montréal
See details and how to joinNCT07902518
No phaseTaking people
Supporting Patients by Family Education in Psychotic Illness: A Prospective Cohort Study
Where
Edmonton
Age
17 years to 27 years
People
113
Run by
University of Alberta
See details and how to joinNCT05500001
No phaseTaking people
The ATP Project (Antipsychotic-TEP-Psychosis)
Where
Sherbrooke
Age
18 years to 35 years
People
18
Run by
Université de Sherbrooke
See details and how to joinNCT06651112
Phase 3Not yet taking people in Canada
Stratification and Treatment in Early Psychosis Study - PROMOTE
Where
Montreal
Age
12 years to 35 years
People
586 worldwide
Run by
University of Oxford
See details and how to joinNCT07434973
No phaseTaking people
Multimodal Intervention to Support Hospital-to-Community Transition in Bipolar Disorder
Where
Hamilton
Age
18 years to 35 years
People
10
Run by
McMaster University
See details and how to joinNCT07213492
Phase 2Taking people
A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis
Where
Brampton, Lévis, London, Toronto
Age
55 years to 90 years
People
300 worldwide
Run by
MapLight Therapeutics
See details and how to joinNCT06887192 · EU 2024-519820-26-00
No phaseTaking people
Investigating the Neural Correlates of Cognitive Function in Psychosis Patients and Non-Psychiatric Controls With Cannabis Use
Where
Montreal
Age
16 years to 80 years
People
134
Run by
Douglas Mental Health University Institute
See details and how to joinNCT05445180
No phaseTaking people
Accelerated Neuromodulation Therapy and Neurocomputational Biomarkers in Individuals at Clinical High Risk for Psychosis
Where
Verdun
Age
18 years to 34 years
People
40
Run by
Douglas Mental Health University Institute
See details and how to joinNCT07786714
Phase 4Taking people
Switching From Twice-Daily to Once-Daily Clozapine Dosing in Schizophrenia
Where
Toronto
Age
18 years and over
People
30
Run by
Centre for Addiction and Mental Health
See details and how to joinNCT02639702
No phaseTaking people
Accelerated Neuromodulation Therapy for Negative Symptoms of Schizophrenia
Where
Montreal, Québec, Verdun
Age
18 years to 65 years
People
75
Run by
Douglas Mental Health University Institute
See details and how to joinNCT07428460
No phaseEnrolling by invitation
A Trial of Group Cognitive Behavioral Therapy for Psychosis (the Feeling Safe Programme)
Where
Ottawa
Age
18 years and over
People
50
Run by
The Royal Ottawa Mental Health Centre
See details and how to joinNCT07408934
Phase 4Taking people
Biomarkers to Enhance Early Schizophrenia Treatment
Where
Toronto
Age
18 years to 35 years
People
180 worldwide
Run by
Northwell Health
See details and how to joinNCT06969755
Phase 3Taking people
A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)
Where
Montreal, Toronto, Whitby
Age
55 years to 90 years
People
325 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT06947941
No phaseNot yet taking people in Canada
Exploring the Genetics of Schizophrenia in Manitoba
Where
Winnipeg
Age
18 years and over
People
1,500
Run by
University of Manitoba
See details and how to joinNCT07656870
No phaseTaking people
Recovery With Exogenous Ketones and Antipsychotics
Where
Sherbrooke
Age
18 years to 35 years
People
15
Run by
Université de Sherbrooke
See details and how to joinNCT07122531
No phaseTaking people
REFLECT: A Novel Group-Based Compassion-Focussed Cognitive Behavioural Approach to Core Beliefs in Psychosis
Where
Scarborough Village
Age
18 years and over
People
38
Run by
University of Toronto
See details and how to joinNCT07569471
No phaseTaking people
Heat Stress in Individuals With Schizophrenia
Where
Ottawa
Age
18 years to 85 years
People
10
Run by
University of Ottawa
See details and how to joinNCT07383324
No phaseTaking people
Examining the Efficacy of a Virtual Reality Cognitive Remediation Program for People Living With Psychosis
Where
Ottawa
Age
18 years to 60 years
People
52
Run by
The Royal Ottawa Mental Health Centre
See details and how to joinNCT05973110
Phase 4Taking people
"Extended" (Alternate Day) Antipsychotic Dosing
Where
Toronto
Age
18 years and over
People
120
Run by
Centre for Addiction and Mental Health
See details and how to joinNCT04478838
Phase 4Taking people
Cannabis Potency Effects on Brain White Matter in Early Phase Psychosis
Where
Halifax, St. John's
Age
18 years to 25 years
People
24
Run by
Nova Scotia Health Authority
See details and how to joinNCT07001878
No phaseTaking people
Effects of Action-Based Cognitive Remediation on Substance Misuse in Early Phase Psychosis
Where
Halifax, St. John's
Age
16 years to 30 years
People
50
Run by
Nova Scotia Health Authority
See details and how to joinNCT07056894
No phaseTaking people
Effects of NAC on Symptoms of CHR Patients
Where
Toronto
Age
16 years to 35 years
People
90
Run by
Centre for Addiction and Mental Health
See details and how to joinNCT05142735
No phaseTaking people
Brain Imaging of Cognition Inn Schizophrenia and Depression
Where
Ottawa
Age
18 years to 60 years
People
90
Run by
The Royal Ottawa Mental Health Centre
See details and how to joinNCT04159662