Mindfulness Program to Ease Stress in Adults With Depression and High Blood Pressure
Tests a mindfulness stress program in African American adults with depression and high blood pressure.
Plain-language title generated from the registry record
Registry title: Community-based Approach to Lowering Stress Through Mindfulness
Key facts
- Where
- Chicago, United StatesSee the site
Where in United States
- The Salvation Army Ray and Joan Kroc Corps Community Center ChicagoChicago, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Northwestern University
- Trial code
- NCT06987799
- Record updated
- 13 April 2026
- Original description
The goal of this clinical trial is to test a culturally adapted mindfulness-based stress reduction intervention in a community setting for African American adults with high blood pressure (hypertension) and depression. The main questions it aims to answer are:Read full original descriptionShow less
Addressing Depression for African American Adults With Hypertension: Applying Community-Engaged Implementation Science
The goal of this clinical trial is to test a culturally adapted mindfulness-based stress reduction intervention in a community setting for African American adults with high blood pressure (hypertension) and depression. The main questions it aims to answer are:
* Does participation in a culturally adapted mindfulness-based intervention improve depressive symptoms? * Does participation in a culturally adapted mindfulness-based intervention improve blood pressure control? * Is the intervention acceptable, appropriate, and feasible as delivered in a community setting?
Participants will:
* Participate in an 8-week group-based mindfulness intervention (CALM-Chicago). During intervention sessions, participants will learn about mindfulness and stress management and complete mindfulness-based activities, such as guided deep breathing and meditation. * Complete surveys online * Have their blood pressure measured with a non-invasive blood pressure cuff * Attend 1 focus group (optional)
Inclusion: ≥18 years old; Lives, works, or spends much of their time in the South Side of Chicago neighborhood; Self-reports diagnosis of hypertension or high blood pressure by a clinician; Endorses elevated depressive symptoms as Patient Health Questionnaire (PHQ)-9 scores ≥10; Not taking antidepressant medication or stable on antidepressant medication for ≥6 months as self-reported.
Exclusion: Severe mental illness (e.g., bipolar disorder, psychosis); <18 years old; Current suicidal ideation (PHQ-9 item 9) or recent (past 6 months) suicide attempt; Unable to provide informed consent or complete study activities in English.