Kidney Cell Metabolism and Scarring in Several Kidney Diseases
Studies kidney tubule metabolism in adults with ANCA vasculitis and other kidney diseases.
Plain-language title generated from the registry record
Registry title: Epithelial Dysmetabolism and Renal Fibrosis in ANCA Vasculitis
Key facts
- Where
- Paris, FranceSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 90 years old?
Source: NCT07010250, who can take part
Where in France
- Georges-Pompidou European Hospital, AP-HPParis, FranceTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Assistance Publique - Hôpitaux de Paris
- Trial code
- NCT07010250
- Record updated
- 30 June 2026
- Original description
The project is to explore in humans the hypothesis of the link between the alteration of tubulo-interstitial metabolism and the rate of deterioration of renal function by comparing various nephropathies.Read full original descriptionShow less
Epithelial Dysmetabolism and Renal Fibrosis in ANCA Vasculitis
The project is to explore in humans the hypothesis of the link between the alteration of tubulo-interstitial metabolism and the rate of deterioration of renal function by comparing various nephropathies.
Inclusion: Patients with an indication for initial diagnostic PBR on native kidney; 18 ans ≥ Age ≤ 90 ans; Affiliation to french health insurance; Patient having given consent; For the ANCA vasculitis group:; Diagnosis of ANCA vasculitis retained on renal biopsy with ANCA anti-proteinase 3 (PR3) or ANCA anti-myeloperoxidase (MPO); For the control groups:; Diagnosis retained after the renal biopsy; Interstitial Nephritis; Or glomerular nephropathy such as minimal change nephropathy; Or Segmental hyalinosis in itscollapsing form; Or Extramembranous Glomerulopathy,; Or glomerulopathy with mesangial IgA deposits; Or diabetic nephropathy.
Exclusion: Kidney transplant patient; Patient on dialysis (hemodialysis or peritoneal dialysis); Patient under legal protection, guardianship or curatorship; Pregnancy or breastfeeding; Enrollement in an interventional study except studies relating to ANCA vasculitis and nephropathy with mesangial IgA deposits.