Magnetic Stimulation Tested for Depression in People With Schizophrenia
Tests repeated magnetic brain stimulation for depressive symptoms in adults with schizophrenia.
Plain-language title generated from the registry record
Registry title: Bilateral Prefrontal and Insular TMS for Depression in Schizophrenia
Key facts
- Where
- Houston, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 60 years old?
Source: NCT07060066, who can take part
Where in United States
- The University of Texas Health Science Center at HoustonHouston, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- The University of Texas Health Science Center, Houston
- Trial code
- NCT07060066
- Record updated
- 5 August 2026
- Original description
The purpose of this study is to provide an effective repetitive transcranial magnetic stimulation (rTMS) treatment for depressive symptoms in patients with schizophrenia. Schizophrenia patients with depressive symptoms will be exposed to rTMS to improve their symptoms.Read full original descriptionShow less
Bilateral Prefrontal and Insular TMS for Depression in Schizophrenia
The purpose of this study is to provide an effective repetitive transcranial magnetic stimulation (rTMS) treatment for depressive symptoms in patients with schizophrenia. Schizophrenia patients with depressive symptoms will be exposed to rTMS to improve their symptoms.
Inclusion: Male and female ages between ages 18-60 years; Ability to give written informed consent (age 18 or above); Diagnosed with schizophrenia-spectrum disorder and Evaluation to Sign Consent (ESC) above 10; Score of Calgary depression scale for schizophrenia (CDSS) ≥ 3.
Exclusion: Significant alcohol or other drug use other than nicotine or marijuana dependence; Inability to refrain from using alcohol and/or marijuana 24 hours or more prior to experiments; Any major medical illnesses that may affect normal brain functioning. Examples of these conditions include, but are not limited to: stroke, repeated seizure, history of significant head trauma with cognitive sequela, CNS infection or tumor, other significant brain neurological conditions; For MRI, inability to participate in the MRI scanning due to metallic devices or objects (cardiac pacemaker or neurostimulator, some artificial joints, metal pins, surgical clips or other implanted metal parts) or declining to get in the scanner; Inability to sign informed consent; Pregnancy, as classified by a woman of child-bearing potential who is not using a contraceptive and has missed a menstrual period; or by self-report; or by positive urine pregnancy test; Failed TMS safety questionnaire.