Following People With Ulcerative Colitis Over One Year in Bordeaux
Follows adults with ulcerative colitis over one year, collecting blood samples and biopsies.
Plain-language title generated from the registry record
Registry title: Cohort of Patients With Ulcerative Colitis or Polyps Followed in CHU de Bordeaux Associated With a Biocollection - COLIBRI
Key facts
- Where
- Pessac, FranceSee the site
Where in France
- CHU de BordeauxPessac, FranceNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University Hospital, Bordeaux
- Trial code
- NCT07082231
- Record updated
- 24 July 2025
- Original description
Ulcerative colitis (UC) is a chronic disease characterized by acute episodes of bloody diarrhea with varying degrees of severity. The most feared event, acute severe UC, can lead to life-threatening and systemic complications. Little is known about the determinants of severity in UC. The investigators hypothesize that distinct severity phenotypes of UC arise from intricated host-microbiota mechanisms influencing repair mechanisms. Our first and main objective is to study the natural history of UC during a one-year time period in a cohort of patients.Read full original descriptionShow less
Cohort of Patients With Ulcerative Colitis or Polyps Followed in CHU de Bordeaux Associated With a Biocollection - COLIBRI
Ulcerative colitis (UC) is a chronic disease characterized by acute episodes of bloody diarrhea with varying degrees of severity. The most feared event, acute severe UC, can lead to life-threatening and systemic complications. Little is known about the determinants of severity in UC. The investigators hypothesize that distinct severity phenotypes of UC arise from intricated host-microbiota mechanisms influencing repair mechanisms. Our first and main objective is to study the natural history of UC during a one-year time period in a cohort of patients.
Inclusion criteria:; General Inclusion Criteria:; Patients covered by a social security system; French-speaking patients; Patients aged ≥18 years; Patients who have provided free, informed, and written consent (no later than the inclusion day and before any research-related examination); Specific Inclusion Criteria for the UC Group:; Patients diagnosed with ulcerative colitis (UC) according to the European Crohn's and Colitis Organisation (ECCO) guidelines; Patients undergoing lower gastrointestinal endoscopy or rectocolic surgery; Non-UC Patients with Polyps Group:; Patients undergoing colonoscopy with resection of hyperplastic polyps in the rectum, sessile serrated lesions, or adenomas >2 cm; Exclusion criteria:; Patients with perianal, ileal lesions, or endoscopic features of colonic lesions suggestive of Crohn's disease; Pregnant or breastfeeding women; Patients under legal protection or unable to provide informed consent; Patients deprived of liberty by judicial or administrative decision, hospitalized without consent, or admitted to a healthcare or social institution for reasons unrelated to the study.