Repetitive Transcranial Magnetic Stimulation Treatment of Stimulant Use Disorder

Who can take part

• Must be a U.S. Veteran
• Structured Clinical Interview for DSM Disorders (SCID) confirmed diagnosis of SUD, severe
• Last use of stimulants >2 and <8 weeks
• Stable medication regimen (no change in dose or agents between 2 weeks prior to the start of and throughout the treatment phase of the study)
• Stable medical health

Who cannot take part

• History of prior adverse reaction to Transcranial magnetic stimulation (TMS)
• Implants or medical devices incompatible with TMS
• For subjects participating in functional magnetic resonance imaging (fMRI) scans, presence of ferromagnetic material in their body or taking DAergic medications
• On medications thought to significantly lower seizure threshold, e.g. clozapine, chlorpromazine, clomipramine, and bupropion > 400mg/day
• Seizure disorder or conditions known to substantially increase risk for seizures
• Acute or unstable chronic medical illness that would affect participation or compliance in the study, e.g. unstable angina
• Unstable psychiatric symptoms that precludes consistent participation in the study, e.g. active current suicidal intent or plan; severe psychosis
• Other substance use disorder not in remission
• Chronic or recurring Axis I psychotic disorders
• Pregnant or lactating female