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Lab Models Built From Tumor Samples of People With Sarcoma or Cancer Spread

Uses leftover tumor samples from people with sarcoma or cancer spread to build lab models.

Plain-language title generated from the registry record
Registry title: Development of Innovative Preclinical Ex Vivo Models for the Study of Sarcomas and Metastases From Solid Tumors

Key facts

Where
Bologna, ItalySee the site

Where in Italy

  • Istituto Ortopedico RizzoliBologna, ItalyTaking people

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Trial details

Who runs it
Istituto Ortopedico Rizzoli
Trial code
NCT07112989
Record updated
8 August 2025
Original description
The goal of this observational study is to learn how tumor tissue and blood samples from patients with sarcomas or metastases can be used to create laboratory models that help researchers study cancer behavior and test new treatments. Participants diagnosed with sarcoma or with bone or lung metastases from solid tumors will donate leftover tumor tissue and blood collected during their regular medical care. These samples will be used in the lab to build 3D models of the tumor, test drugs, and identify genetic and molecular markers. No treatments or procedures will be given as part of the study.Read full original descriptionShow less

Development of Innovative Preclinical Ex Vivo Models for the Study of Sarcomas and Metastases From Solid Tumors

The goal of this observational study is to learn how tumor tissue and blood samples from patients with sarcomas or metastases can be used to create laboratory models that help researchers study cancer behavior and test new treatments. Participants diagnosed with sarcoma or with bone or lung metastases from solid tumors will donate leftover tumor tissue and blood collected during their regular medical care. These samples will be used in the lab to build 3D models of the tumor, test drugs, and identify genetic and molecular markers. No treatments or procedures will be given as part of the study.

Inclusion: Patients (male or female) diagnosed with sarcoma or with bone or lung metastases from solid tumors; Age between 0 and 85 years; Availability of sufficient and adequate biological material (tumor tissue and/or blood); Signed informed consent for biobanking (BIOTUM); Signed informed consent for use of tissue and blood samples in this study.

Exclusion: Diagnosis other than sarcoma or metastases from solid tumors; Missing signed informed consent(s).

ClinicalTrials.gov NCT07112989