Childhood cancers trials in Italy

In Italy 205 Also abroad 2459

205 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)
Where
Bologna, Brescia, Milan, Naples, Siena, Verona
Age
12 years and over
People
355 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT04924075 · EU 2023-504853-11-00
Phase 3Taking people
Study of Volrustomig in Women With High Risk Locally Advanced Cervical Cancer (eVOLVE-Cervical)
Where
Bologna, Catania, Florence, Lecco, Milan, Monza, Naples, Rome, Turin
Age
15 years and over
People
800 worldwide
Run by
AstraZeneca
See details and how to joinNCT06079671 · EU 2023-504374-38-00
Phase 2Taking people
Study to Determine the Efficacy and Safety of Asciminib in Pediatric Patients With Ph+ CML-CP
Where
Padova, Roma
Age
1 year to 18 years
People
50 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07354074
Phase 2/3Taking people
A Clinical Trial of MK-1045 in People With B-cell Acute Lymphoblastic Leukemia (MK-1045-005)
Where
Bergamo, Bologna, Genoa, Rome, Turin
Age
12 years and over
People
340 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT07570173 · EU 2025-522267-15-00
Phase 2Taking people
A Study of Belzutifan in Adolescent Participants With Solid Tumors (MK-9999-01E/LIGHTBEAM-U01)
Where
Milan, Rome, Turin
Age
12 years to 17 years
People
15 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT07700758 · EU 2025-524515-37-00
Phase 4Taking people
Asciminib Roll-over Study
Where
Genoa, Meldola, Milan, Pisa, Rome, Turin
Age
7 years to 100 years
People
347 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT04877522 · EU 2023-507557-16-00
Phase 1/2Taking people
A Study of Neladalkib (NVL-655) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1)
Where
Ancona, Bari, Milan, Padova, Ravenna, Rome
Age
12 years and over
People
840 worldwide
Run by
Nuvalent Inc.
See details and how to joinNCT05384626 · EU 2024-514266-39-00
Phase 1/2Taking people
A Study to Evaluate Glofitamab Monotherapy and Glofitamab + Chemoimmunotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Mature B-Cell Non-Hodgkin Lymphoma
Where
Rome, Turin
Age
6 months to 30 years
People
65 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT05533775
Phase 1/2Taking people
A Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Anti-Tumor Activity of Glofitamab in Monotherapy and in Combination with Chemoimmunotherapy in Pediatric and Young Adult Participants with Relapsed/Refractory Mature B-Cell Non-Hodgkin Lymphoma
Where
Rome, Turin
Age
Up to 17 years
People
37 worldwide
Run by
F. Hoffmann-La Roche AG
See details and how to join2023-504264-41-00 · EU 2023-504264-41-00
No phaseTaking people
Observational Study in Localized Osteosarcoma
Where
Aviano, Bari, Bologna, Candiolo, Catania, Florence, Genova, Milan, Padova, Palermo, Pisa, Roma, Trieste
Age
Up to 40 years
People
120
Run by
Italian Sarcoma Group
See details and how to joinNCT04890067
No phaseTaking people
Definition of Mutational Profile of Papillary Thyroid Tumors by Mass-ARRAY
Where
Milan
People
600
Run by
Istituto Auxologico Italiano
See details and how to joinNCT05766098
Phase 2Taking people
Clinical Study in Adult and Young Adult Patients With Advanced Desmoplastic Small Round Cell Tumor (DSRCT) ISG-TULIPS
Where
Candiolo, Milan, Padova, Prato, Rome
Age
15 years and over
People
20 worldwide
Run by
Italian Sarcoma Group
See details and how to joinNCT07328425 · EU 2024-519261-21-00
Phase 2/3Taking people
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
Where
Bergamo, Bologna, Genoa, Milan, Monza, Naples, Rome, Rozzano, Turin, Udine
People
1,541 worldwide
Run by
Celgene
See details and how to joinNCT03435796 · EU 2023-504201-36-00
No phaseNot yet taking people in Italy
Assessment of Intelligent Algorithms for Detection, Diagnosis and Risk Stratification of Tumors of the Kidney and Prostate
Where
Naples
People
50 worldwide
Run by
Aristotle University Of Thessaloniki
See details and how to joinNCT07888322
Phase 1/2Taking people
Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)
Where
Milan, Rome, Turin
Age
6 months to 25 years
People
90 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT06395103 · EU 2023-507178-41-00
Phase 1/2Taking people
A Study of Ifinatamab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01D/LIGHTBEAM-U01)
Where
Milan, Rome, Turin
Age
1 month to 17 years
People
134 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT07630974 · EU 2025-522339-32-00
No phaseTaking people
Met Non Small Cell Cancer Registry (MOMENT)
Where
Milan, Misterbianco, Modena, Naples, Rome, Torino, Varese
People
700 worldwide
Run by
EMD Serono Research & Development Institute, Inc.
See details and how to joinNCT05376891
No phaseNot yet taking people in Italy
Twenty-five Years of Advanced RadioTherapy at San Raffaele Hospital
Where
Milan
Age
6 years to 90 years
People
10,000
Run by
IRCCS San Raffaele
See details and how to joinNCT07894900
No phaseTaking people
Establishment of a Novel Flow Cytometric Diagnostic Assay to Effectively Evaluate Immune Reconstitution After Hematopoietic Stem Cell Transplantation for Acute Lymphoblastic Leukemia
Where
Monza, Padova
People
150 worldwide
Run by
Fondazione Matilde Tettamanti Menotti De Marchi Onlus
See details and how to joinNCT07899840
Phase 1Taking people
Phase I Trial to Determine the Dose and Evaluate the PK and Safety of Lutetium Lu 177 Edotreotide Therapy in Pediatric Participants With SSTR-positive Tumors
Where
Milan
Age
24 months to 18 years
People
20 worldwide
Run by
ITM Solucin GmbH
See details and how to joinNCT06441331 · EU 2024-512831-66-00
No phaseTaking people
Master Framework For Relapse or Refractory Acute Myeloid Leukemia
Where
Ancona, Bologna, Brescia, Brindisi, Busto Arsizio, Castelfranco Veneto, Como, Cremona, Cuneo, Ferrara, Florence, Genova, Meldola, Milan, Naples, Novara, Padova, Palermo, Perugia, Pescara, Ravenna, Rimini, Roma, Salerno, Torino, Vicenza
Age
6 years and over
People
4,000 worldwide
Run by
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
See details and how to joinNCT06459024
Phase 3Taking people
International Study for Treatment of Childhood Relapsed Precursor B-Cell ALL 2020 (IntReALL BCP 2020)
Where
Ancona, Bari, Bergamo, Bologna, Cagliari, Catania, Florence, Genoa, Monza, Naples, Padova, Palermo, Pavia, Rome, San Giovanni Rotondo, Trieste, Turin, Verona
Age
1 year to 64 years
People
750 worldwide
Run by
Charite University, Berlin, Germany
See details and how to joinNCT07476729 · EU 2023-509392-17-00
Phase 3Taking people
Fight Osteosarcoma Through European Research Evolving Study Platform From Diagnosis to Relapse
Where
Bologna, Genova, Milan, Padova, Pisa, Roma, Torino
Age
4 years and over
People
530 worldwide
Run by
Gustave Roussy, Cancer Campus, Grand Paris
See details and how to joinNCT07871864
Phase 1/2Taking people
Study of AZD3632 Monotherapy or in Combination With Anticancer Agents in Participants With Advanced Haematologic Malignancies With KMT2Ar, NPM1m, or Other Genotypes Associated With HOX Overexpression
Where
Bologna, Ravenna
Age
16 years and over
People
85 worldwide
Run by
AstraZeneca
See details and how to joinNCT07155226 · EU 2025-521299-76-00
No phaseNot yet taking people in Italy
Healthcare Providers' Attitudes Toward Oncology Patients With Mental Disorders
Where
Aviano, Bari, Meldola, Padova, Rionero in Vulture
People
1,000
Run by
Istituto Oncologico Veneto IRCCS
See details and how to joinNCT07748221