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Tests financial rewards for taking long-acting injectable medicine after hospital stay

Tests money incentives to support injection adherence in adults with serious mental illness.

Plain-language title generated from the registry record
Registry title: Incentives and Long-Acting Injectable Adherence After Involuntary Hospitalization

Key facts

Where
McKeesport and Pittsburgh, United StatesSee the 6 sites

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 65 years old?

Source: NCT07130500, who can take part

Where in United States

  • UPMC Mon YoughMcKeesport, United StatesNo longer taking part
  • Pittsburgh MercyPittsburgh, United StatesNo longer taking part
  • UPMC Bellefield TowersPittsburgh, United StatesNo longer taking part
  • UPMC Franklin BuildingPittsburgh, United StatesNo longer taking part
  • UPMC Oxford BuildingPittsburgh, United StatesNo longer taking part
  • UPMC Western Psychiatric HospitalPittsburgh, United StatesNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Stanford University
Trial code
NCT07130500
Record updated
23 October 2026
Original description
This study is a randomized controlled trial evaluating the impact of financial incentives on medication adherence among individuals with schizophrenia, schizoaffective disorder, or bipolar disorder and/or co-occurring substance use disorder who are recently discharged from involuntary hospitalization or are at high risk of future involuntary hospitalization. Participants will be randomized to receive financial incentives for adherence to long-acting injectable medications or to a control group.Read full original descriptionShow less

Can Financial Incentives Improve Medication Adherence and Patient Outcomes After Involuntary Hospitalization?

This study is a randomized controlled trial evaluating the impact of financial incentives on medication adherence among individuals with schizophrenia, schizoaffective disorder, or bipolar disorder and/or co-occurring substance use disorder who are recently discharged from involuntary hospitalization or are at high risk of future involuntary hospitalization. Participants will be randomized to receive financial incentives for adherence to long-acting injectable medications or to a control group.

Inclusion: Diagnosis of schizophrenia, schizoaffective disorder, and/or bipolar disorder; Recent (within 12 months) involuntary hospitalization or high risk of future hospitalization; Eligible for medication (antipsychotic or SUD-related) with an LAI formulation; Allegheny County, PA resident; Receiving or assigned to treatment at clinics participating in this study.

Exclusion: Lack of injectable formulation for prescribed medication; Aged under 18 or 65 or older.

ClinicalTrials.gov NCT07130500