Vitamin D, Bone Markers and Weight in Children With Low-Energy Fractures
Compares blood bone markers and weight between children with and without low-energy fractures.
Plain-language title generated from the registry record
Registry title: Bone Outcomes, Obesity, Sunlight, and Trauma in Children
Key facts
- Where
- Brixen and Meran, ItalySee the 2 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 3 and 15 years old?
Source: NCT07143552, who can take part
Where in Italy
- Kaiser Franz Joseph HospitalBrixen, ItalyTaking people
- Franz Tappeiner HospitalMeran, ItalyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Paracelsus Medical University
- Trial code
- NCT07143552
- Record updated
- 3 September 2025
- Original description
Prospective case-control study of children (3-15 years) after low-energy trauma. We compare serum bone metabolic markers (25OHD, PTH, ALP, calcium, phosphate), BMI/percentile, and dietary calcium intake between fracture and non-fracture presentations. Blood is collected within 7 days (non-fasting; samples on ice for PTH). Primary aim: association of ALP and calcium with fracture status; secondary aims: vitamin D status, BMI percentile, and a composite Bone Risk Score (≥3). Analyses: group comparisons, logistic regression, ROC.Read full original descriptionShow less
A Prospective Case-Control Study of Vitamin D Status, Bone Metabolic Markers, and Overweight in Pediatric Low-Energy Fractures
Prospective case-control study of children (3-15 years) after low-energy trauma. We compare serum bone metabolic markers (25OHD, PTH, ALP, calcium, phosphate), BMI/percentile, and dietary calcium intake between fracture and non-fracture presentations. Blood is collected within 7 days (non-fasting; samples on ice for PTH). Primary aim: association of ALP and calcium with fracture status; secondary aims: vitamin D status, BMI percentile, and a composite Bone Risk Score (≥3). Analyses: group comparisons, logistic regression, ROC.
Inclusion: 3-15 years; low-energy trauma; cases = radiographic fracture; controls = no fracture.
Exclusion: corticosteroids/bisphosphonates; chronic renal/liver disease; neuromuscular disorders; primary hypo-/hyperparathyroidism; hypophosphatemic rickets; unclear diagnosis/treatment.