Vitamin D, Bone Markers and Weight in Children With Low-Energy Fractures
Compares blood bone markers and weight between children with and without low-energy fractures.
Plain-language title generated from the registry record
Registry title: Bone Outcomes, Obesity, Sunlight, and Trauma in Children
Key facts
- Where
- Brixen and Meran, ItalySee the 2 sites
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for children aged 3 to 15 years who had a low-energy injury. Some have a broken bone on X-ray, and some do not.
- Age
- 3 to 15 years
- Sex
- Boys and girls can both join.
- Disease stage
- Low-energy injury. Cases have a fracture seen on X-ray; controls have no fracture.
- Earlier treatment
- Children taking corticosteroids or bisphosphonates cannot join.
Main reasons for not taking part
- Long-term kidney or liver disease
- Primary hypoparathyroidism or hyperparathyroidism
- Hypophosphatemic rickets
- Nerve and muscle disorders
- Taking corticosteroids or bisphosphonates
Read by machine on 12 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 3 and 15 years old?
Source: NCT07143552, who can take part
Where in Italy
- Kaiser Franz Joseph HospitalBrixen, ItalyContact: Andrea Cosentino, MDTaking people
- Franz Tappeiner HospitalMeran, ItalyContact: Andrea Cosentino, MDTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Paracelsus Medical University
- Trial code
- NCT07143552
- Record updated
- 3 September 2025
- Original description
Prospective case-control study of children (3-15 years) after low-energy trauma. We compare serum bone metabolic markers (25OHD, PTH, ALP, calcium, phosphate), BMI/percentile, and dietary calcium intake between fracture and non-fracture presentations. Blood is collected within 7 days (non-fasting; samples on ice for PTH). Primary aim: association of ALP and calcium with fracture status; secondary aims: vitamin D status, BMI percentile, and a composite Bone Risk Score (≥3). Analyses: group comparisons, logistic regression, ROC.Read full original descriptionShow less
A Prospective Case-Control Study of Vitamin D Status, Bone Metabolic Markers, and Overweight in Pediatric Low-Energy Fractures
Prospective case-control study of children (3-15 years) after low-energy trauma. We compare serum bone metabolic markers (25OHD, PTH, ALP, calcium, phosphate), BMI/percentile, and dietary calcium intake between fracture and non-fracture presentations. Blood is collected within 7 days (non-fasting; samples on ice for PTH). Primary aim: association of ALP and calcium with fracture status; secondary aims: vitamin D status, BMI percentile, and a composite Bone Risk Score (≥3). Analyses: group comparisons, logistic regression, ROC.
Inclusion: 3-15 years; low-energy trauma; cases = radiographic fracture; controls = no fracture.
Exclusion: corticosteroids/bisphosphonates; chronic renal/liver disease; neuromuscular disorders; primary hypo-/hyperparathyroidism; hypophosphatemic rickets; unclear diagnosis/treatment.